Human Gene MISP3 (uc002mxz.3)
  Description: Homo sapiens uncharacterized MISP3 (MISP3), non-coding RNA.
Transcript (Including UTRs)
   Position: hg19 chr19:14,183,821-14,185,874 Size: 2,054 Total Exon Count: 3 Strand: +
Coding Region
   Position: hg19 chr19:14,184,122-14,185,535 Size: 1,414 Coding Exon Count: 3 

Page IndexSequence and LinksPrimersGene AllelesRNA-Seq ExpressionMicroarray Expression
RNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther NamesModel Information
Methods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr19:14,183,821-14,185,874)mRNA (may differ from genome)Protein (219 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaAlphaFoldBioGPS
EnsemblExonPrimerGeneCardsGeneNetworkLynxMGI
neXtProtPubMedTreefamUniProtKB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 14.16 RPKM in Brain - Cerebellum
Total median expression: 226.86 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -131.20301-0.436 Picture PostScript Text
3' UTR -110.72339-0.327 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  Pfam Domains:
PF15304 - A-kinase anchor protein 2 C-terminus

ModBase Predicted Comparative 3D Structure on Q96FF7
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Descriptions from all associated GenBank mRNAs
  LF208174 - JP 2014500723-A/15677: Polycomb-Associated Non-Coding RNAs.
BC011002 - Homo sapiens hypothetical protein LOC113230, mRNA (cDNA clone IMAGE:3946502).
LF373238 - JP 2014500723-A/180741: Polycomb-Associated Non-Coding RNAs.
JD371867 - Sequence 352891 from Patent EP1572962.
JD384311 - Sequence 365335 from Patent EP1572962.
JD118913 - Sequence 99937 from Patent EP1572962.
JD075769 - Sequence 56793 from Patent EP1572962.
JD398471 - Sequence 379495 from Patent EP1572962.
JD501397 - Sequence 482421 from Patent EP1572962.
HZ460821 - WO 2015190584-A/318: Kit or device and method for detecting prostate cancer.
HZ461549 - WO 2015190586-A/362: Kit and method for detecting colon cancer.
HZ462188 - WO 2015190591-A/343: Kit and method for detecting breast cancer.
HZ463304 - WO 2015194535-A/398: Kit and method for detecting stomach cancer.
HZ463770 - WO 2015194610-A/206: Kit and method for detecting lung cancer.
HZ464509 - WO 2015194615-A/327: Kit or device and method for detecting hepatic cancer.
LY497192 - KR 1020170016485-A/362: COLORECTAL CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD.
LY497671 - KR 1020170018409-A/206: KIT OR DEVICE FOR DETECTING LUNG CANCER, AND LUNG CANCER DETECTION METHOD.
LY498410 - KR 1020170018411-A/327: LIVER CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD.
LY499191 - KR 1020170018412-A/343: BREAST CANCER DETECTION KIT OR DEVICE, AND METHOD FOR DETECTING BREAST CANCER.
LY500117 - KR 1020170019425-A/398: STOMACH CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD.
LY500694 - KR 1020170016490-A/318: PROSTATE CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD.
LZ238658 - WO 2017171048-A/319: Kit, device and method for detecting early pancreatic cancer or precancerous lesion of pancreas.
MS869613 - Sequence 318 from Patent EP3156483.
MS880506 - Sequence 343 from Patent EP3156498.
MS884379 - Sequence 362 from Patent EP3156499.
MS885236 - Sequence 398 from Patent EP3156503.
MS996737 - Sequence 206 from Patent EP3159416.
HZ460635 - WO 2015190584-A/132: Kit or device and method for detecting prostate cancer.
HZ461357 - WO 2015190586-A/170: Kit and method for detecting colon cancer.
HZ461914 - WO 2015190591-A/69: Kit and method for detecting breast cancer.
HZ463105 - WO 2015194535-A/199: Kit and method for detecting stomach cancer.
HZ463597 - WO 2015194610-A/33: Kit and method for detecting lung cancer.
HZ464286 - WO 2015194615-A/104: Kit or device and method for detecting hepatic cancer.
LY497000 - KR 1020170016485-A/170: COLORECTAL CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD.
LY497498 - KR 1020170018409-A/33: KIT OR DEVICE FOR DETECTING LUNG CANCER, AND LUNG CANCER DETECTION METHOD.
LY498187 - KR 1020170018411-A/104: LIVER CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD.
LY498917 - KR 1020170018412-A/69: BREAST CANCER DETECTION KIT OR DEVICE, AND METHOD FOR DETECTING BREAST CANCER.
LY499918 - KR 1020170019425-A/199: STOMACH CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD.
LY500508 - KR 1020170016490-A/132: PROSTATE CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD.
LZ238406 - WO 2017171048-A/67: Kit, device and method for detecting early pancreatic cancer or precancerous lesion of pancreas.
MS869427 - Sequence 132 from Patent EP3156483.
MS880232 - Sequence 69 from Patent EP3156498.
MS884187 - Sequence 170 from Patent EP3156499.
MS885037 - Sequence 199 from Patent EP3156503.
MS996564 - Sequence 33 from Patent EP3159416.
BC000492 - Homo sapiens cDNA clone IMAGE:2820069, partial cds.
LF373237 - JP 2014500723-A/180740: Polycomb-Associated Non-Coding RNAs.
JD360574 - Sequence 341598 from Patent EP1572962.
JD157862 - Sequence 138886 from Patent EP1572962.
JD263704 - Sequence 244728 from Patent EP1572962.
JD434552 - Sequence 415576 from Patent EP1572962.
JD520324 - Sequence 501348 from Patent EP1572962.
JD037455 - Sequence 18479 from Patent EP1572962.
MA608815 - JP 2018138019-A/180741: Polycomb-Associated Non-Coding RNAs.
MA608814 - JP 2018138019-A/180740: Polycomb-Associated Non-Coding RNAs.
MA443751 - JP 2018138019-A/15677: Polycomb-Associated Non-Coding RNAs.
MA806184 - WO 2018199275-A/444: Kit, device and method for detection of ovary tumor.
MA805907 - WO 2018199275-A/167: Kit, device and method for detection of ovary tumor.
MA822696 - WO 2019004436-A/509: Kit, device, and method for detection of lung cancer.
MA822359 - WO 2019004436-A/172: Kit, device, and method for detection of lung cancer.
LY616422 - KR 1020180129785-A/319: KIT OR DEVICE FOR DETECTING EARLY STAGE PANCREATIC CANCER OR PANCREATIC CANCER PRECURSOR LESIONS AND DETECTION METHOD THEREFOR.
LY616170 - KR 1020180129785-A/67: KIT OR DEVICE FOR DETECTING EARLY STAGE PANCREATIC CANCER OR PANCREATIC CANCER PRECURSOR LESIONS AND DETECTION METHOD THEREFOR.
MB472849 - WO 2019208671-A/248: Kit or device and method for detecting bladder cancer.
MB472606 - WO 2019208671-A/5: Kit or device and method for detecting bladder cancer.

-  Other Names for This Gene
  Alternate Gene Symbols: LOC113230, NR_024282, Q96FF7, YS003_HUMAN
UCSC ID: uc002mxz.3
RefSeq Accession: NR_024282
Protein: Q96FF7 (aka YS003_HUMAN)

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NR_024282.1
exon count: 3CDS single in 3' UTR: no RNA size: 1329
ORF size: 660CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 860.00frame shift in genome: no % Coverage: 97.82
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.