Description: Homo sapiens RIO kinase 1 (RIOK1), transcript variant 1, mRNA. RefSeq Summary (NM_031480): The protein encoded by this gene competes with pICln for inclusion in the protein arginine methyltransferase 5 complex. This complex targets substrates for dimethylation. The encoded protein is essential for the last steps in the maturation of 40S subunits. [provided by RefSeq, Jan 2017]. Transcript (Including UTRs) Position: hg19 chr6:7,390,062-7,418,270 Size: 28,209 Total Exon Count: 17 Strand: + Coding Region Position: hg19 chr6:7,390,236-7,417,674 Size: 27,439 Coding Exon Count: 17
ID:RIOK1_HUMAN DESCRIPTION: RecName: Full=Serine/threonine-protein kinase RIO1; EC=2.7.11.1; AltName: Full=RIO kinase 1; CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein. SIMILARITY: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. SIMILARITY: Contains 1 protein kinase domain.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
SCOP Domains: 56112 - Protein kinase-like (PK-like)
ModBase Predicted Comparative 3D Structure on Q9BRS2
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
