Human Gene FAM193A (uc010ick.3)
  Description: Homo sapiens family with sequence similarity 193, member A (FAM193A), transcript variant 1, mRNA.
Transcript (Including UTRs)
   Position: hg19 chr4:2,597,828-2,734,302 Size: 136,475 Total Exon Count: 20 Strand: +
Coding Region
   Position: hg19 chr4:2,597,829-2,733,595 Size: 135,767 Coding Exon Count: 20 

Page IndexSequence and LinksPrimersGenetic AssociationsCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureProtein StructureOther SpeciesmRNA Descriptions
Other NamesModel InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr4:2,597,828-2,734,302)mRNA (may differ from genome)Protein (1424 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
GeneNetworkHGNCLynxMGIPubMedTreefam
UniProtKBWikipediaBioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Genetic Association Studies of Complex Diseases and Disorders
  Genetic Association Database (archive): FAM193A
CDC HuGE Published Literature: FAM193A

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 20.23 RPKM in Testis
Total median expression: 420.61 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
3' UTR -255.01707-0.361 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  Pfam Domains:
PF15914 - FAM193 family C-terminal

ModBase Predicted Comparative 3D Structure on P78312-2
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologGenome BrowserNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
  Ensembl   
  Protein Sequence   
  Alignment   

-  Descriptions from all associated GenBank mRNAs
  AB385173 - Synthetic construct DNA, clone: pF1KB7007, Homo sapiens C4orf8 gene for C4orf8 protein, complete cds, without stop codon, in Flexi system.
AK308449 - Homo sapiens cDNA, FLJ98397.
AB000459 - Homo sapiens mRNA, complete cds, clone: RES4-22A.
AB000460 - Homo sapiens mRNA, complete cds, clone:RES4-22B.
AB000461 - Homo sapiens mRNA, complete cds, clone:RES4-22C.
BC136646 - Homo sapiens chromosome 4 open reading frame 8, mRNA (cDNA clone MGC:168259 IMAGE:9020636), complete cds.
BC144337 - Homo sapiens cDNA clone IMAGE:9052857.
BC144339 - Homo sapiens cDNA clone IMAGE:9052859.
BC144340 - Homo sapiens chromosome 4 open reading frame 8, mRNA (cDNA clone MGC:177877 IMAGE:9052860), complete cds.
JD389963 - Sequence 370987 from Patent EP1572962.
JD125094 - Sequence 106118 from Patent EP1572962.
JD054817 - Sequence 35841 from Patent EP1572962.
JD494005 - Sequence 475029 from Patent EP1572962.
AB001563 - Homo sapiens mRNA for RES4-22D, partial cds.
AF040966 - Homo sapiens unknown protein IT14 mRNA, partial cds.
AK303732 - Homo sapiens cDNA FLJ51441 partial cds.
JD333503 - Sequence 314527 from Patent EP1572962.
AK307430 - Homo sapiens cDNA, FLJ97378.
JD270359 - Sequence 251383 from Patent EP1572962.
JD445396 - Sequence 426420 from Patent EP1572962.
JD116519 - Sequence 97543 from Patent EP1572962.
JD399285 - Sequence 380309 from Patent EP1572962.
JD231859 - Sequence 212883 from Patent EP1572962.
JD480729 - Sequence 461753 from Patent EP1572962.
JD494255 - Sequence 475279 from Patent EP1572962.
JD206488 - Sequence 187512 from Patent EP1572962.
JD192954 - Sequence 173978 from Patent EP1572962.
JD090640 - Sequence 71664 from Patent EP1572962.
JD390945 - Sequence 371969 from Patent EP1572962.
JD246271 - Sequence 227295 from Patent EP1572962.
JD480268 - Sequence 461292 from Patent EP1572962.
JD211432 - Sequence 192456 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: AB385173, C4orf8, NM_003704, NP_003695, P78312-2, RES4-22
UCSC ID: uc010ick.3
RefSeq Accession: NM_003704
Protein: P78312-2, splice isoform of P78312

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: AB385173.1
exon count: 20CDS single in 3' UTR: no RNA size: 4289
ORF size: 4275CDS single in intron: no Alignment % ID: 99.95
txCdsPredict score: 7034.00frame shift in genome: no % Coverage: 99.63
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.