The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9Y2R4
Front
Top
Side
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
AK025721 - Homo sapiens cDNA: FLJ22068 fis, clone HEP11588, highly similar to AF077033 Homo sapiens putative ATP-dependent RNA helicase ROK1 mRNA. BC041785 - Homo sapiens DEAD (Asp-Glu-Ala-Asp) box polypeptide 52, mRNA (cDNA clone MGC:32662 IMAGE:4808288), complete cds. AK027425 - Homo sapiens cDNA FLJ14519 fis, clone NT2RM1000852, highly similar to Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-). AK001652 - Homo sapiens cDNA FLJ10790 fis, clone NT2RP4000518, weakly similar to ATP-DEPENDENT RNA HELICASE ROK1. JD175053 - Sequence 156077 from Patent EP1572962. AF077033 - Homo sapiens putative ATP-dependent RNA helicase ROK1 mRNA, complete cds. JD088607 - Sequence 69631 from Patent EP1572962. JD096805 - Sequence 77829 from Patent EP1572962. AK001245 - Homo sapiens cDNA FLJ10383 fis, clone NT2RM2002100, highly similar to Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-). AJ010840 - Homo sapiens mRNA for ATP-dependent RNA helicase, partial. AB208938 - Homo sapiens mRNA for ATP-dependent RNA helicase ROK1 isoform a variant protein. JD555149 - Sequence 536173 from Patent EP1572962. JD550853 - Sequence 531877 from Patent EP1572962. JD155677 - Sequence 136701 from Patent EP1572962. JD285387 - Sequence 266411 from Patent EP1572962. JD398613 - Sequence 379637 from Patent EP1572962. JD070398 - Sequence 51422 from Patent EP1572962. JD420384 - Sequence 401408 from Patent EP1572962. JD254661 - Sequence 235685 from Patent EP1572962. JD529906 - Sequence 510930 from Patent EP1572962. JD176059 - Sequence 157083 from Patent EP1572962. JD280570 - Sequence 261594 from Patent EP1572962. JD492196 - Sequence 473220 from Patent EP1572962. KJ898343 - Synthetic construct Homo sapiens clone ccsbBroadEn_07737 DDX52 gene, encodes complete protein. BC006489 - Homo sapiens DEAD (Asp-Glu-Ala-Asp) box polypeptide 52, mRNA (cDNA clone IMAGE:3687438), partial cds. AK093661 - Homo sapiens cDNA FLJ36342 fis, clone THYMU2006666. AX748248 - Sequence 1773 from Patent EP1308459. CU692030 - Synthetic construct Homo sapiens gateway clone IMAGE:100022333 5' read DDX52 mRNA. BC012557 - Homo sapiens DEAD (Asp-Glu-Ala-Asp) box polypeptide 52, mRNA (cDNA clone IMAGE:4296354), with apparent retained intron. JD240666 - Sequence 221690 from Patent EP1572962. JD326250 - Sequence 307274 from Patent EP1572962. JD233145 - Sequence 214169 from Patent EP1572962. JD233420 - Sequence 214444 from Patent EP1572962. JD203679 - Sequence 184703 from Patent EP1572962.
Biochemical and Signaling Pathways
Reactome (by CSHL, EBI, and GO)
Protein Q9Y2R4 (Reactome details) participates in the following event(s):
R-HSA-6790906 EMG1 of the SSU processome methylates pseudouridine-1248 of 18S rRNA yielding N(1)-methylpseudouridine-1248 R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6790901 rRNA modification in the nucleus and cytosol R-HSA-8868773 rRNA processing in the nucleus and cytosol R-HSA-72312 rRNA processing R-HSA-8953854 Metabolism of RNA