Description: Homo sapiens GPRASP2 readthrough (GPRASP2), mRNA. RefSeq Summary (NM_001199818): This locus represents naturally occurring readthrough transcription among the adjacent armadillo repeat containing, X-linked 5 (ARMCX5), G protein-coupled receptor associated sorting proteins 1 and 2 (GPRASP1 and GPRASP2), basic helix-loop-helix family member b9 (BHLHB9), and long intergenic non-protein coding RNA 630 (LINC00630) genes on chromosome X. Transcripts may make use of multiple alternative promoters and polyadenylation signals in this region. Readthrough transcripts may produce proteins identical to the proteins encoded by GPRASP2 or BHLHB9. [provided by RefSeq, Apr 2017]. Transcript (Including UTRs) Position: hg19 chrX:101,854,276-101,972,661 Size: 118,386 Total Exon Count: 7 Strand: + Coding Region Position: hg19 chrX:101,969,798-101,972,314 Size: 2,517 Coding Exon Count: 1
ID:GASP2_HUMAN DESCRIPTION: RecName: Full=G-protein coupled receptor-associated sorting protein 2; Short=GASP-2; FUNCTION: May play a role in regulation of a variety of G-protein coupled receptors. SUBUNIT: Interacts with cytoplasmic tails of a variety of G- protein coupled receptors such as muscarinic acetylcholine receptor M1/CHRM1 and calcitonin receptor/CALCR. TISSUE SPECIFICITY: Expressed in the brain. SIMILARITY: Belongs to the GPRASP family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q96D09
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.