Description: Homo sapiens cytokine induced apoptosis inhibitor 1 (CIAPIN1), mRNA. RefSeq Summary (NM_020313): CIAPIN1 is a cytokine-induced inhibitor of apoptosis with no relation to apoptosis regulatory molecules of the BCL2 (MIM 151430) or CASP (see MIM 147678) families. Expression of CIAPIN1 is dependent on growth factor stimulation (Shibayama et al., 2004 [PubMed 14970183]).[supplied by OMIM, Mar 2008]. Transcript (Including UTRs) Position: hg19 chr16:57,462,087-57,481,369 Size: 19,283 Total Exon Count: 9 Strand: - Coding Region Position: hg19 chr16:57,463,082-57,474,840 Size: 11,759 Coding Exon Count: 8
ID:CPIN1_HUMAN DESCRIPTION: RecName: Full=Anamorsin; AltName: Full=Cytokine-induced apoptosis inhibitor 1; AltName: Full=Fe-S cluster assembly protein DRE2 homolog; FUNCTION: May be required for the maturation of extramitochondrial Fe/S proteins (By similarity). Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells (By similarity). SUBCELLULAR LOCATION: Cytoplasm. Nucleus. TISSUE SPECIFICITY: Ubiquitously expressed. Highly expressed in heart, liver and pancreas. MISCELLANEOUS: 'Ana-mors-in' means 'anti-death molecule' in Latin. SIMILARITY: Belongs to the anamorsin family. SEQUENCE CAUTION: Sequence=AAC24312.1; Type=Erroneous gene model prediction;
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q6FI81
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
