Human Gene FMR1NB (uc004fcm.3)
Description: Homo sapiens fragile X mental retardation 1 neighbor (FMR1NB), mRNA.Transcript (Including UTRs) Position: hg19 chrX:147,062,849-147,108,187 Size: 45,339 Total Exon Count: 6 Strand: +Coding Region Position: hg19 chrX:147,062,923-147,106,520 Size: 43,598 Coding Exon Count: 5
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: FMR1N_HUMAN DESCRIPTION: RecName: Full=Fragile X mental retardation 1 neighbor protein; AltName: Full=Cancer/testis antigen 37; Short=CT37; AltName: Full=Sarcoma antigen NY-SAR-35;SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (Potential).TISSUE SPECIFICITY: Testis-specific. Expressed in melanoma, sarcoma, lung, breast, bladder, esophageal and ovarian cancers.SIMILARITY: Contains 1 P-type (trefoil) domain.
Primer design for this transcript
Comparative Toxicogenomics Database (CTD)
The following chemicals interact with this gene
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR000519 - P_trefoilModBase Predicted Comparative 3D Structure on Q8N0W7 The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse Rat Zebrafish D. melanogaster C. elegans S. cerevisiae
No ortholog No ortholog No ortholog No ortholog No ortholog No ortholog Gene Details Gene Sorter
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
BC034320 - Homo sapiens fragile X mental retardation 1 neighbor, mRNA (cDNA clone MGC:42907 IMAGE:4836772), complete cds.AY211917 - Homo sapiens sarcoma antigen NY-SAR-35 mRNA, complete cds.AK098602 - Homo sapiens cDNA FLJ25736 fis, clone TST05681.JD055090 - Sequence 36114 from Patent EP1572962.HQ447121 - Synthetic construct Homo sapiens clone IMAGE:100070408; CCSB002328_01 fragile X mental retardation 1 neighbor (FMR1NB) gene, encodes complete protein.KJ895701 - Synthetic construct Homo sapiens clone ccsbBroadEn_05095 FMR1NB gene, encodes complete protein.JD090246 - Sequence 71270 from Patent EP1572962.LF380539 - JP 2014500723-A/188042: Polycomb-Associated Non-Coding RNAs.LF380551 - JP 2014500723-A/188054: Polycomb-Associated Non-Coding RNAs.JD203260 - Sequence 184284 from Patent EP1572962.JD172580 - Sequence 153604 from Patent EP1572962.JD287682 - Sequence 268706 from Patent EP1572962.JD161795 - Sequence 142819 from Patent EP1572962.LF380552 - JP 2014500723-A/188055: Polycomb-Associated Non-Coding RNAs.MA616116 - JP 2018138019-A/188042: Polycomb-Associated Non-Coding RNAs.MA616128 - JP 2018138019-A/188054: Polycomb-Associated Non-Coding RNAs.MA616129 - JP 2018138019-A/188055: Polycomb-Associated Non-Coding RNAs.
Other Names for This Gene
Alternate Gene Symbols: D3DWT3, FMR1N_HUMAN, NM_152578, NP_689791, Q8N0W7UCSC ID: uc004fcm.3RefSeq Accession: NM_152578 Protein: Q8N0W7
(aka FMR1N_HUMAN)CCDS: CCDS14683.1
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
NM_152578.2
exon count:
6 CDS single in 3' UTR:
no
RNA size:
1021 ORF size:
768 CDS single in intron:
no
Alignment % ID:
100.00 txCdsPredict score:
1459.00 frame shift in genome:
no
% Coverage:
100.00 has start codon:
yes
stop codon in genome:
no
# of Alignments:
1 has end codon:
yes
retained intron:
no
# AT/AC introns
0 selenocysteine:
no
end bleed into intron:
0 # strange splices:
0
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Methods, Credits, and Use Restrictions
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US Server
