Human Gene C12orf76 (uc001tqe.2)
  Description: Homo sapiens chromosome 12 open reading frame 76 (C12orf76), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr12:110,478,983-110,511,439 Size: 32,457 Total Exon Count: 4 Strand: -
Coding Region
   Position: hg19 chr12:110,480,179-110,496,889 Size: 16,711 Coding Exon Count: 3 

Page IndexSequence and LinksPrimersCTDGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureOther SpeciesmRNA DescriptionsOther NamesModel Information
Methods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr12:110,478,983-110,511,439)mRNA (may differ from genome)Protein (96 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaBioGPS
EnsemblEntrez GeneExonPrimerGeneCardsGeneNetworkH-INV
HGNCLynxMGIPubMedBioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 14.75 RPKM in Brain - Spinal cord (cervical c-1)
Total median expression: 211.20 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -92.60292-0.317 Picture PostScript Text
3' UTR -333.011196-0.278 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
      
      
      

-  Descriptions from all associated GenBank mRNAs
  BC046185 - Homo sapiens FLJ40142 protein, mRNA (cDNA clone IMAGE:5416162), partial cds.
AK097461 - Homo sapiens cDNA FLJ40142 fis, clone TESTI2012922.
BC133010 - Homo sapiens FLJ40142 protein, mRNA (cDNA clone MGC:164641 IMAGE:40147032), complete cds.
BC133012 - Homo sapiens FLJ40142 protein, mRNA (cDNA clone MGC:164643 IMAGE:40147034), complete cds.
BC144372 - Homo sapiens cDNA clone IMAGE:9052893.
KJ900725 - Synthetic construct Homo sapiens clone ccsbBroadEn_10119 C12orf76 gene, encodes complete protein.
AK094845 - Homo sapiens cDNA FLJ37526 fis, clone BRCAN2010374, weakly similar to P2X PURINOCEPTOR 7.
AK021447 - Homo sapiens cDNA FLJ11385 fis, clone HEMBA1000520.
BC041968 - Homo sapiens FLJ40142 protein, mRNA (cDNA clone IMAGE:5302663).
AF086409 - Homo sapiens full length insert cDNA clone ZD76H04.
JD533419 - Sequence 514443 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: BC046185, NM_207435, NP_997318, uc001tqe.1
UCSC ID: uc001tqe.2
RefSeq Accession: NM_207435

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: BC046185.1
exon count: 4CDS single in 3' UTR: no RNA size: 1788
ORF size: 291CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 693.50frame shift in genome: no % Coverage: 98.60
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.