Human Gene LYZL2 (uc001ivk.3) Description and Page Index
Description: Homo sapiens lysozyme-like 2 (LYZL2), mRNA. RefSeq Summary (NM_183058): Lysozymes (see LYZ; MIM 153450), especially C-type lysozymes, are well-recognized bacteriolytic factors widely distributed in the animal kingdom and play a mainly protective role in host defense. LYZL2 is a member of a family of lysozyme-like genes (Zhang et al., 2005 [PubMed 16014814]).[supplied by OMIM, Apr 2009]. CCDS Note: The coding region has been updated to start at a downstream in-frame start codon that is supported by conservation data. ##Evidence-Data-START## Transcript exon combination :: BC066294.1, AF139543.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream AUG and CDS extension is not conserved RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## Transcript (Including UTRs) Position: hg19 chr10:30,900,708-30,918,647 Size: 17,940 Total Exon Count: 5 Strand: - Coding Region Position: hg19 chr10:30,900,884-30,918,634 Size: 17,751 Coding Exon Count: 5
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
Pfam Domains: PF00062 - C-type lysozyme/alpha-lactalbumin family
ModBase Predicted Comparative 3D Structure on Q7Z4W2-2
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.