Human Gene VXN (uc003xwg.3)
Description: Homo sapiens chromosome 8 open reading frame 46 (VXN), mRNA.
Transcript (Including UTRs)
Position: hg19 chr8:67,405,491-67,430,759 Size: 25,269 Total Exon Count: 6 Strand: +
Coding Region
Position: hg19 chr8:67,405,884-67,428,311 Size: 22,428 Coding Exon Count: 6
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: CH046_HUMAN
DESCRIPTION: RecName: Full=Uncharacterized protein C8orf46;
SEQUENCE CAUTION: Sequence=AAH28400.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAG37870.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Primer design for this transcript
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
Pfam Domains: PF15505 - Domain of unknown function (DUF4648)
ModBase Predicted Comparative 3D Structure on Q8TAG6
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse Rat Zebrafish D. melanogaster C. elegans S. cerevisiae
No ortholog No ortholog No ortholog No ortholog No ortholog No ortholog
Gene Details
Gene Sorter
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
JD450465 - Sequence 431489 from Patent EP1572962.AK315486 - Homo sapiens cDNA, FLJ96549.BC028400 - Homo sapiens chromosome 8 open reading frame 46, mRNA (cDNA clone MGC:33510 IMAGE:4816822), complete cds.AK308800 - Homo sapiens cDNA, FLJ98841.JD532144 - Sequence 513168 from Patent EP1572962.AK096336 - Homo sapiens cDNA FLJ39017 fis, clone NT2RP7002064.AK294261 - Homo sapiens cDNA FLJ52537 complete cds.JD178450 - Sequence 159474 from Patent EP1572962.GQ129359 - Synthetic construct Homo sapiens clone HAIB:100068690; DKFZo004E0436 chromosome 8 open reading frame 46 protein (C8orf46) gene, partial cds.GQ129360 - Synthetic construct Homo sapiens clone HAIB:100068593; DKFZo008E0435 chromosome 8 open reading frame 46 protein (C8orf46) gene, complete cds.KJ901087 - Synthetic construct Homo sapiens clone ccsbBroadEn_10481 C8orf46 gene, encodes complete protein.AK055047 - Homo sapiens cDNA FLJ30485 fis, clone BRAWH2000082.JD528593 - Sequence 509617 from Patent EP1572962.JD037115 - Sequence 18139 from Patent EP1572962.JD263472 - Sequence 244496 from Patent EP1572962.JD038315 - Sequence 19339 from Patent EP1572962.JD499363 - Sequence 480387 from Patent EP1572962.JD250095 - Sequence 231119 from Patent EP1572962.JD086198 - Sequence 67222 from Patent EP1572962.JD156096 - Sequence 137120 from Patent EP1572962.JD313893 - Sequence 294917 from Patent EP1572962.JD486642 - Sequence 467666 from Patent EP1572962.JD317319 - Sequence 298343 from Patent EP1572962.JD400323 - Sequence 381347 from Patent EP1572962.JD241003 - Sequence 222027 from Patent EP1572962.JD082093 - Sequence 63117 from Patent EP1572962.JD354897 - Sequence 335921 from Patent EP1572962.JD305336 - Sequence 286360 from Patent EP1572962.JD550895 - Sequence 531919 from Patent EP1572962.JD360218 - Sequence 341242 from Patent EP1572962.JD544734 - Sequence 525758 from Patent EP1572962.JD353450 - Sequence 334474 from Patent EP1572962.JD242529 - Sequence 223553 from Patent EP1572962.JD414082 - Sequence 395106 from Patent EP1572962.JD548959 - Sequence 529983 from Patent EP1572962.JD477493 - Sequence 458517 from Patent EP1572962.JD193428 - Sequence 174452 from Patent EP1572962.JD133212 - Sequence 114236 from Patent EP1572962.JD100102 - Sequence 81126 from Patent EP1572962.JD528583 - Sequence 509607 from Patent EP1572962.JD313633 - Sequence 294657 from Patent EP1572962.JD541152 - Sequence 522176 from Patent EP1572962.JD426713 - Sequence 407737 from Patent EP1572962.JD499688 - Sequence 480712 from Patent EP1572962.JD286880 - Sequence 267904 from Patent EP1572962.JD096163 - Sequence 77187 from Patent EP1572962.JD175764 - Sequence 156788 from Patent EP1572962.JD415386 - Sequence 396410 from Patent EP1572962.JD375375 - Sequence 356399 from Patent EP1572962.JD525879 - Sequence 506903 from Patent EP1572962.JD150693 - Sequence 131717 from Patent EP1572962.JD473554 - Sequence 454578 from Patent EP1572962.JD145630 - Sequence 126654 from Patent EP1572962.
Other Names for This Gene
Alternate Gene Symbols: B2RDC3, B4DFU4, C8orf46, C9J814, C9JCS3, CH046_HUMAN, NM_152765, NP_689978, Q8TAG6UCSC ID: uc003xwg.3RefSeq Accession: NM_152765
Protein: Q8TAG6
(aka CH046_HUMAN)
CCDS: CCDS6191.2
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
NM_152765.3
exon count:
6 CDS single in 3' UTR:
no
RNA size:
3471
ORF size:
624 CDS single in intron:
no
Alignment % ID:
100.00
txCdsPredict score:
1338.00 frame shift in genome:
no
% Coverage:
99.83
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
no
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
0 # strange splices:
0
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Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.