Human Gene OOSP2 (uc001nol.3)
  Description: Homo sapiens placenta-specific 1-like (OOSP2), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr11:59,807,748-59,815,516 Size: 7,769 Total Exon Count: 4 Strand: +
Coding Region
   Position: hg19 chr11:59,807,933-59,814,546 Size: 6,614 Coding Exon Count: 4 

Page IndexSequence and LinksUniProtKB CommentsPrimersGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA Descriptions
Other NamesModel InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr11:59,807,748-59,815,516)mRNA (may differ from genome)Protein (158 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
GeneNetworkH-INVHPRDLynxMGIneXtProt
PubMedTreefamUniProtKBBioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: PLACL_HUMAN
DESCRIPTION: RecName: Full=Placenta-specific 1-like protein; Flags: Precursor;
SUBCELLULAR LOCATION: Secreted (Potential).
SIMILARITY: Belongs to the PLAC1 family.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 13.18 RPKM in Testis
Total median expression: 13.18 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -45.62185-0.247 Picture PostScript Text
3' UTR -202.13970-0.208 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  ModBase Predicted Comparative 3D Structure on Q86WS3
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
      
      
      

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Cellular Component:
GO:0005576 extracellular region


-  Descriptions from all associated GenBank mRNAs
  BC048121 - Homo sapiens placenta-specific 1-like, mRNA (cDNA clone MGC:57403 IMAGE:5266642), complete cds.
LP895809 - Sequence 673 from Patent EP3253886.
HM005455 - Homo sapiens clone HTL-T-142 testicular tissue protein Li 142 mRNA, complete cds.
BC036256 - Homo sapiens placenta-specific 1-like, mRNA (cDNA clone MGC:43628 IMAGE:5270384), complete cds.
AK093517 - Homo sapiens cDNA FLJ36198 fis, clone TESTI2028242, weakly similar to Mus musculus EPCS26 mRNA.
AX748179 - Sequence 1704 from Patent EP1308459.
KJ905044 - Synthetic construct Homo sapiens clone ccsbBroadEn_14438 PLAC1L gene, encodes complete protein.
JD242288 - Sequence 223312 from Patent EP1572962.
JD086894 - Sequence 67918 from Patent EP1572962.
JD556864 - Sequence 537888 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: NM_173801, NP_776162, PLAC1L, PLACL_HUMAN, Q86WS3, Q8N9U6, TMEM122
UCSC ID: uc001nol.3
RefSeq Accession: NM_173801
Protein: Q86WS3 (aka PLACL_HUMAN)
CCDS: CCDS7979.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_173801.3
exon count: 4CDS single in 3' UTR: no RNA size: 1646
ORF size: 477CDS single in intron: no Alignment % ID: 99.88
txCdsPredict score: 1100.00frame shift in genome: no % Coverage: 99.15
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.