ID:EMC4_HUMAN DESCRIPTION: RecName: Full=ER membrane protein complex subunit 4; AltName: Full=Cell proliferation-inducing gene 17 protein; AltName: Full=Transmembrane protein 85; FUNCTION: May mediate anti-apoptotic activity. SUBUNIT: Component of the ER membrane protein complex (EMC). SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Isoform 1 is expressed in brain and heart. Isoform 2 is expressed in heart. SIMILARITY: Belongs to the EMC4 family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Pfam Domains: PF06417 - Protein of unknown function (DUF1077)
ModBase Predicted Comparative 3D Structure on Q5J8M3
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
