Description: Homo sapiens family with sequence similarity 71, member A (FAM71A), mRNA. RefSeq Summary (NM_153606): This gene encodes a protein that interacts with the Rab2B small GTPase and may be important for integrity of the Golgi body. A knockdown of this gene induces fragmentation of the Golgi, similar to the effect seen with a knockdown of the Rab2B small GTPase. The encoded protein has an N-terminal Rab-binding domain specific for Rab2B. [provided by RefSeq, Feb 2017]. Transcript (Including UTRs) Position: hg19 chr1:212,797,789-212,800,120 Size: 2,332 Total Exon Count: 1 Strand: + Coding Region Position: hg19 chr1:212,798,220-212,800,004 Size: 1,785 Coding Exon Count: 1
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Pfam Domains: PF12480 - Protein of unknown function (DUF3699)
ModBase Predicted Comparative 3D Structure on Q8IYT1
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
