Human Gene GUSBP1 (uc010iub.3)
  Description: Homo sapiens glucuronidase, beta pseudogene 1 (GUSBP1), transcript variant 3, non-coding RNA.
Transcript (Including UTRs)
   Position: hg19 chr5:21,459,589-21,497,305 Size: 37,717 Total Exon Count: 6 Strand: +
Coding Region
   Position: hg19 chr5:21,459,669-21,497,231 Size: 37,563 Coding Exon Count: 6 

Page IndexSequence and LinksPrimersCTDGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther Names
Model InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr5:21,459,589-21,497,305)mRNA (may differ from genome)Protein (182 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaAlphaFold
BioGPSEnsemblExonPrimerGeneCardsH-INVHGNC
LynxMGIPubMedUniProtKB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 3.96 RPKM in Brain - Cerebellar Hemisphere
Total median expression: 66.36 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -25.6080-0.320 Picture PostScript Text
3' UTR -18.7074-0.253 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR013812 - Glyco_hydro_2/20_Ig-like
IPR006102 - Glyco_hydro_2_Ig-like

SCOP Domains:
49303 - beta-Galactosidase/glucuronidase domain

ModBase Predicted Comparative 3D Structure on B4DZD7
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
      
      
      

-  Descriptions from all associated GenBank mRNAs
  AK302866 - Homo sapiens cDNA FLJ58963 complete cds, highly similar to Beta-glucuronidase-like protein SMA3.
AK290693 - Homo sapiens cDNA FLJ75429 complete cds, highly similar to Homo sapiens glucuronidase, beta-like 2 (GUSBL2), transcript variant 1, mRNA.
BC147000 - Homo sapiens glucuronidase, beta pseudogene, mRNA (cDNA clone IMAGE:9056928).
AK095656 - Homo sapiens cDNA FLJ38337 fis, clone FCBBF3026692, moderately similar to Homo sapiens WD repeat domain 70 (WDR70), mRNA.
BC070045 - Homo sapiens cDNA clone IMAGE:30348136, partial cds.
BC038977 - Homo sapiens glucuronidase, beta pseudogene, mRNA (cDNA clone IMAGE:5555860), with apparent retained intron.
BC052307 - Homo sapiens cDNA clone IMAGE:6574963, partial cds.
BC094818 - Homo sapiens cDNA clone IMAGE:6383257.
LF335953 - JP 2014500723-A/143456: Polycomb-Associated Non-Coding RNAs.
JD045900 - Sequence 26924 from Patent EP1572962.
L40519 - Homo sapiens (clone DR2) mRNA fragment.
DQ583004 - Homo sapiens piRNA piR-50116, complete sequence.
JD268451 - Sequence 249475 from Patent EP1572962.
JD559997 - Sequence 541021 from Patent EP1572962.
JD390493 - Sequence 371517 from Patent EP1572962.
MA571530 - JP 2018138019-A/143456: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: B4DZD7, B4DZD7_HUMAN, NR_027028
UCSC ID: uc010iub.3
RefSeq Accession: NR_027028
Protein: B4DZD7

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NR_027028.2
exon count: 6CDS single in 3' UTR: no RNA size: 703
ORF size: 549CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 924.00frame shift in genome: no % Coverage: 100.00
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.