Human Gene TIMM29 (uc002mqd.2)
  Description: Homo sapiens chromosome 19 open reading frame 52 (TIMM29), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr19:11,039,424-11,040,916 Size: 1,493 Total Exon Count: 2 Strand: +
Coding Region
   Position: hg19 chr19:11,039,499-11,040,378 Size: 880 Coding Exon Count: 2 

Page IndexSequence and LinksPrimersGene AllelesRNA-Seq ExpressionMicroarray Expression
RNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther Names
Model InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr19:11,039,424-11,040,916)mRNA (may differ from genome)Protein (260 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaAlphaFoldBioGPS
EnsemblEntrez GeneExonPrimerGeneCardsGeneNetworkH-INV
HPRDLynxMGIneXtProtOMIMPubMed
TreefamUniProtKBBioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 10.99 RPKM in Testis
Total median expression: 310.99 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -23.6075-0.315 Picture PostScript Text
3' UTR -181.50538-0.337 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR019322 - DUF2366

Pfam Domains:
PF10171 - Translocase of the Inner Mitochondrial membrane 29

ModBase Predicted Comparative 3D Structure on Q9BSF4
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologGenome BrowserGenome BrowserGenome BrowserNo ortholog
Gene Details  Gene DetailsGene Details 
Gene Sorter  Gene SorterGene Sorter 
  EnsemblFlyBaseWormBase 
  Protein SequenceProtein SequenceProtein Sequence 
  AlignmentAlignmentAlignment 

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0005515 protein binding

Biological Process:
GO:0015031 protein transport
GO:0045039 protein import into mitochondrial inner membrane

Cellular Component:
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005758 mitochondrial intermembrane space
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0042721 mitochondrial inner membrane protein insertion complex


-  Descriptions from all associated GenBank mRNAs
  BC011833 - Homo sapiens chromosome 19 open reading frame 52, mRNA (cDNA clone MGC:20497 IMAGE:3941883), complete cds.
BC007244 - Homo sapiens chromosome 19 open reading frame 52, mRNA (cDNA clone MGC:15460 IMAGE:2966591), complete cds.
BC005075 - Homo sapiens chromosome 19 open reading frame 52, mRNA (cDNA clone MGC:13012 IMAGE:3534875), complete cds.
KJ899906 - Synthetic construct Homo sapiens clone ccsbBroadEn_09300 C19orf52 gene, encodes complete protein.
JD024956 - Sequence 5980 from Patent EP1572962.
JD389752 - Sequence 370776 from Patent EP1572962.
JD546254 - Sequence 527278 from Patent EP1572962.
JD134658 - Sequence 115682 from Patent EP1572962.
JD268156 - Sequence 249180 from Patent EP1572962.
JD166582 - Sequence 147606 from Patent EP1572962.
JD323152 - Sequence 304176 from Patent EP1572962.
JD044850 - Sequence 25874 from Patent EP1572962.
JD263174 - Sequence 244198 from Patent EP1572962.
JD158674 - Sequence 139698 from Patent EP1572962.
JD546202 - Sequence 527226 from Patent EP1572962.
JD221707 - Sequence 202731 from Patent EP1572962.
JD184773 - Sequence 165797 from Patent EP1572962.
JD330687 - Sequence 311711 from Patent EP1572962.
JD291624 - Sequence 272648 from Patent EP1572962.
JD373432 - Sequence 354456 from Patent EP1572962.
JD145693 - Sequence 126717 from Patent EP1572962.
JD507910 - Sequence 488934 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: C19orf52, CS052_HUMAN, NM_138358, NP_612367, Q96EY6, Q96IT8, Q9BSF4
UCSC ID: uc002mqd.2
RefSeq Accession: NM_138358
Protein: Q9BSF4 (aka CS052_HUMAN)
CCDS: CCDS12252.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_138358.2
exon count: 2CDS single in 3' UTR: no RNA size: 1414
ORF size: 783CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 1766.00frame shift in genome: no % Coverage: 98.73
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.