Description: Homo sapiens thymus, brain and testes associated (TBATA), mRNA. RefSeq Summary (NM_152710): This gene encodes a protein that regulates thymic epithelial cell proliferation and thymus size. It has been identified as a ligand for the class I human leukocyte antigen (HLA-I) in thymus. Studies of the orthologous mouse protein suggest that it may also play a role in spermatid differentiation, as well as in neuronal morphogenesis and synaptic plasticity. Polymorphisms in this gene are associated with susceptibility for multiple sclerosis (MS). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]. Transcript (Including UTRs) Position: hg19 chr10:72,530,995-72,545,157 Size: 14,163 Total Exon Count: 11 Strand: - Coding Region Position: hg19 chr10:72,531,132-72,543,135 Size: 12,004 Coding Exon Count: 9
ID:TBATA_HUMAN DESCRIPTION: RecName: Full=Protein TBATA; AltName: Full=Protein SPATIAL; AltName: Full=Stromal protein associated with thymii and lymph node homolog; AltName: Full=Thymus, brain and testes-associated protein; FUNCTION: May play a role in spermatid differentiation (By similarity). Modulates thymic stromal cell proliferation and thymus function (By similarity). SUBCELLULAR LOCATION: Cytoplasm, cytosol (By similarity). SIMILARITY: Belongs to the TBATA family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q96M53
Front
Top
Side
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
