Description: Homo sapiens myoneurin (MYNN), transcript variant 3, mRNA. RefSeq Summary (NM_001185119): This gene encodes a member of the BTB/POZ and zinc finger domain-containing protein family that are involved in the control of gene expression. Alternative splicing results in multiple transcript variants and a pseudogene has been identified on chromosome 14. [provided by RefSeq, Jun 2010]. Transcript (Including UTRs) Position: hg19 chr3:169,492,053-169,507,504 Size: 15,452 Total Exon Count: 6 Strand: + Coding Region Position: hg19 chr3:169,492,084-169,504,466 Size: 12,383 Coding Exon Count: 6
Celiac Disease Patrick C A Dubois et al. Nature genetics 2010, Multiple common variants for celiac disease influencing immune gene expression., Nature genetics.
[PubMed 20190752]
Colorectal Neoplasms Richard S Houlston et al. Nature genetics 2010, Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33., Nature genetics.
[PubMed 20972440]
Multiple Sclerosis Stephen Sawcer et al. Nature 2011, Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis., Nature.
[PubMed 21833088]
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
Pfam Domains: PF00096 - Zinc finger, C2H2 type PF00651 - BTB/POZ domain PF12874 - Zinc-finger of C2H2 type PF13894 - C2H2-type zinc finger PF13912 - C2H2-type zinc finger
ModBase Predicted Comparative 3D Structure on Q9NPC7-2
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
