Human Gene ZNF585B (uc002ofq.3)
Description: Homo sapiens zinc finger protein 585B (ZNF585B), mRNA.
Transcript (Including UTRs)
Position: hg19 chr19:37,672,481-37,701,451 Size: 28,971 Total Exon Count: 5 Strand: -
Coding Region
Position: hg19 chr19:37,676,129-37,698,013 Size: 21,885 Coding Exon Count: 4
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: Z585B_HUMAN
DESCRIPTION: RecName: Full=Zinc finger protein 585B; AltName: Full=zinc finger protein 41-like protein;
FUNCTION: May be involved in transcriptional regulation.SUBCELLULAR LOCATION: Nucleus (Potential).SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein family.SIMILARITY: Contains 21 C2H2-type zinc fingers.SIMILARITY: Contains 1 KRAB domain.SEQUENCE CAUTION: Sequence=BAB55400.1; Type=Erroneous initiation;
Primer design for this transcript
Genetic Association Studies of Complex Diseases and Disorders
Genetic Association Database (archive): ZNF585B
CDC HuGE Published Literature: ZNF585B
Positive Disease Associations: Asthma
Related Studies: Asthma , , .
[PubMed 0 ]
Comparative Toxicogenomics Database (CTD)
The following chemicals interact with this gene
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR001909 - Krueppel-associated_box
IPR007087 - Znf_C2H2
IPR015880 - Znf_C2H2-like
IPR013087 - Znf_C2H2/integrase_DNA-bd
Pfam Domains: PF00096 - Zinc finger, C2H2 type
PF01352 - KRAB box
PF13912 - C2H2-type zinc finger
SCOP Domains: 48695 - Multiheme cytochromes
109640 - KRAB domain (Kruppel-associated box, Pfam 01352)
57667 - C2H2 and C2HC zinc fingers
57889 - Cysteine-rich domain
57903 - FYVE/PHD zinc finger
ModBase Predicted Comparative 3D Structure on Q52M93
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse Rat Zebrafish D. melanogaster C. elegans S. cerevisiae
No ortholog No ortholog No ortholog No ortholog No ortholog No ortholog
Gene Details
Gene Sorter
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
AK098695 - Homo sapiens cDNA FLJ25829 fis, clone TST08126.AK090574 - Homo sapiens cDNA FLJ33255 fis, clone ASTRO2005553.AX746517 - Sequence 42 from Patent EP1308459.BC029737 - Homo sapiens zinc finger protein 585B, mRNA (cDNA clone IMAGE:3864509), partial cds.AK094989 - Homo sapiens cDNA FLJ37670 fis, clone BRHIP2011933, highly similar to Zinc finger protein 585B.AY147015 - Homo sapiens zinc finger protein 41-like protein mRNA, complete cds.AK027834 - Homo sapiens cDNA FLJ14928 fis, clone PLACE1009099, moderately similar to ZINC FINGER PROTEIN 41.AK091586 - Homo sapiens cDNA FLJ34267 fis, clone FEBRA2002707, highly similar to Zinc finger protein 585B.AX747075 - Sequence 600 from Patent EP1308459.JD188629 - Sequence 169653 from Patent EP1572962.JD084043 - Sequence 65067 from Patent EP1572962.JD163901 - Sequence 144925 from Patent EP1572962.JD290911 - Sequence 271935 from Patent EP1572962.JD097364 - Sequence 78388 from Patent EP1572962.BC093625 - Homo sapiens zinc finger protein 585B, mRNA (cDNA clone MGC:120660 IMAGE:7939470), complete cds.EU446556 - Synthetic construct Homo sapiens clone IMAGE:100069942; IMAGE:100011765; FLH257105.01L zinc finger protein 585B (ZNF585B) gene, encodes complete protein.BC051277 - Homo sapiens zinc finger protein 585B, mRNA (cDNA clone IMAGE:6250801), containing frame-shift errors.BC067088 - Homo sapiens zinc finger protein 585B, mRNA (cDNA clone IMAGE:6208925), partial cds.BC080550 - Homo sapiens zinc finger protein 585B, mRNA (cDNA clone IMAGE:6249350).JD084020 - Sequence 65044 from Patent EP1572962.JD314878 - Sequence 295902 from Patent EP1572962.JD314877 - Sequence 295901 from Patent EP1572962.JD314879 - Sequence 295903 from Patent EP1572962.AF024705 - Homo sapiens clone L4-10 zinc finger protein mRNA, partial cds.JD314882 - Sequence 295906 from Patent EP1572962.JD507138 - Sequence 488162 from Patent EP1572962.JD314870 - Sequence 295894 from Patent EP1572962.JD314878 - Sequence 295902 from Patent EP1572962.JD314877 - Sequence 295901 from Patent EP1572962.JD314879 - Sequence 295903 from Patent EP1572962.JD434463 - Sequence 415487 from Patent EP1572962.JD314817 - Sequence 295841 from Patent EP1572962.JD314816 - Sequence 295840 from Patent EP1572962.JD109341 - Sequence 90365 from Patent EP1572962.JD489776 - Sequence 470800 from Patent EP1572962.JD216322 - Sequence 197346 from Patent EP1572962.JD170893 - Sequence 151917 from Patent EP1572962.
Biochemical and Signaling Pathways
Other Names for This Gene
Alternate Gene Symbols: NM_152279, NP_689492, Q52M93, Q8IZD3, Q96JW6, Z585B_HUMANUCSC ID: uc002ofq.3RefSeq Accession: NM_152279
Protein: Q52M93
(aka Z585B_HUMAN)
CCDS: CCDS12500.1
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
NM_152279.3
exon count:
5 CDS single in 3' UTR:
no
RNA size:
6210
ORF size:
2310 CDS single in intron:
no
Alignment % ID:
100.00
txCdsPredict score:
4752.50 frame shift in genome:
no
% Coverage:
100.00
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
yes
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
5520 # strange splices:
0
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Methods, Credits, and Use Restrictions
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