ID:ZN830_HUMAN DESCRIPTION: RecName: Full=Zinc finger protein 830; AltName: Full=Coiled-coil domain-containing protein 16; FUNCTION: May act as a regulator of the cell cycle in embryos by participating in control of M phase (By similarity). SUBCELLULAR LOCATION: Nucleus (By similarity). Note=Excluded from nucleolus (By similarity). PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. SIMILARITY: Contains 1 C2H2-type zinc finger.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q96NB3
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
AK315671 - Homo sapiens cDNA, FLJ96765. AK055707 - Homo sapiens cDNA FLJ31145 fis, clone IMR322001332, weakly similar to NEUROFILAMENT TRIPLET M PROTEIN. AB590460 - Synthetic construct DNA, clone: pFN21AE1138, Homo sapiens ZNF830 gene for zinc finger protein 830, without stop codon, in Flexi system. BC002913 - Homo sapiens zinc finger protein 830, mRNA (cDNA clone IMAGE:3954132), partial cds. BC011584 - Homo sapiens zinc finger protein 830, mRNA (cDNA clone IMAGE:4578213), partial cds. JD488840 - Sequence 469864 from Patent EP1572962. DQ895528 - Synthetic construct Homo sapiens clone IMAGE:100009988; FLH185275.01L; RZPDo839H04145D coiled-coil domain containing 16 (CCDC16) gene, encodes complete protein. KJ903569 - Synthetic construct Homo sapiens clone ccsbBroadEn_12963 ZNF830 gene, encodes complete protein. DQ892326 - Synthetic construct clone IMAGE:100004956; FLH185279.01X; RZPDo839H04146D coiled-coil domain containing 16 (CCDC16) gene, encodes complete protein. BC009044 - Homo sapiens zinc finger protein 830, mRNA (cDNA clone IMAGE:3852758), partial cds. DQ586355 - Homo sapiens piRNA piR-53467, complete sequence. JD280873 - Sequence 261897 from Patent EP1572962. JD048650 - Sequence 29674 from Patent EP1572962. JD501736 - Sequence 482760 from Patent EP1572962. JD297064 - Sequence 278088 from Patent EP1572962. JD281047 - Sequence 262071 from Patent EP1572962.
Biochemical and Signaling Pathways
Reactome (by CSHL, EBI, and GO)
Protein Q96NB3 (Reactome details) participates in the following event(s):
R-HSA-6782004 Assembly of the pre-incision complex in TC-NER R-HSA-6782069 UVSSA:USP7 deubiquitinates ERCC6 R-HSA-6782131 RNA Pol II backtracking in TC-NER R-HSA-6782138 ERCC5 and RPA bind TC-NER site R-HSA-6782211 DNA polymerases delta, epsilon or kappa bind the TC-NER site R-HSA-6782204 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER R-HSA-6782224 3' incision by ERCC5 (XPG) in TC-NER R-HSA-6782227 Ligation of newly synthesized repair patch to incised DNA in TC-NER R-HSA-6782208 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER R-HSA-6782141 Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER R-HSA-6781823 Formation of TC-NER Pre-Incision Complex R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6782135 Dual incision in TC-NER R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-5696398 Nucleotide Excision Repair R-HSA-73894 DNA Repair
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