Human Gene C22orf24 (uc003aly.3)
  Description: Homo sapiens chromosome 22 open reading frame 24 (C22orf24), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr22:32,329,507-32,341,336 Size: 11,830 Total Exon Count: 3 Strand: -
Coding Region
   Position: hg19 chr22:32,330,104-32,334,052 Size: 3,949 Coding Exon Count: 2 

Page IndexSequence and LinksUniProtKB CommentsPrimersGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA Descriptions
Other NamesModel InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr22:32,329,507-32,341,336)mRNA (may differ from genome)Protein (160 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaAlphaFoldBioGPS
EnsemblEntrez GeneExonPrimerGeneCardsGeneNetworkHGNC
HPRDLynxMGIneXtProtPubMedTreefam
UniProtKBBioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: CV024_HUMAN
DESCRIPTION: RecName: Full=Uncharacterized protein C22orf24;
SUBCELLULAR LOCATION: Membrane; Single-pass membrane protein (Potential).

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 0.41 RPKM in Brain - Nucleus accumbens (basal ganglia)
Total median expression: 4.14 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -38.16167-0.229 Picture PostScript Text
3' UTR -226.36597-0.379 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  ModBase Predicted Comparative 3D Structure on Q9Y442
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Cellular Component:
GO:0016020 membrane
GO:0016021 integral component of membrane


-  Descriptions from all associated GenBank mRNAs
  AL050256 - Novel human gene mapping to chomosome 22.
JD273812 - Sequence 254836 from Patent EP1572962.
JD459942 - Sequence 440966 from Patent EP1572962.
JD098431 - Sequence 79455 from Patent EP1572962.
JD384852 - Sequence 365876 from Patent EP1572962.
JD558217 - Sequence 539241 from Patent EP1572962.
JD347106 - Sequence 328130 from Patent EP1572962.
JD519818 - Sequence 500842 from Patent EP1572962.
JD444540 - Sequence 425564 from Patent EP1572962.
JD461020 - Sequence 442044 from Patent EP1572962.
JD423090 - Sequence 404114 from Patent EP1572962.
AK294232 - Homo sapiens cDNA FLJ55838 complete cds.
JD202955 - Sequence 183979 from Patent EP1572962.
AJ704765 - Homo sapiens mRNA for hypothetical protein (C22ORF24_v1), splice variant 1.
AJ704766 - Homo sapiens mRNA for hypothetical protein (C22ORF24_v2), splice variant 2.
JD469892 - Sequence 450916 from Patent EP1572962.
JD520245 - Sequence 501269 from Patent EP1572962.
JD094905 - Sequence 75929 from Patent EP1572962.
JD507899 - Sequence 488923 from Patent EP1572962.
AK315264 - Homo sapiens cDNA, FLJ96273.
JD040921 - Sequence 21945 from Patent EP1572962.
JD374059 - Sequence 355083 from Patent EP1572962.
JD315207 - Sequence 296231 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: B2RCT4, CV024_HUMAN, NM_015372, NP_056187, Q5K3R1, Q9Y442
UCSC ID: uc003aly.3
RefSeq Accession: NM_015372
Protein: Q9Y442 (aka CV024_HUMAN)
CCDS: CCDS46693.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_015372.1
exon count: 3CDS single in 3' UTR: no RNA size: 1247
ORF size: 483CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 790.00frame shift in genome: no % Coverage: 100.00
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.