Human Gene ZNF503 (uc001jxg.3)
Description: Homo sapiens zinc finger protein 503 (ZNF503), mRNA.
Transcript (Including UTRs)
Position: hg19 chr10:77,157,603-77,161,513 Size: 3,911 Total Exon Count: 2 Strand: -
Coding Region
Position: hg19 chr10:77,158,507-77,161,177 Size: 2,671 Coding Exon Count: 2
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: ZN503_HUMAN
DESCRIPTION: RecName: Full=Zinc finger protein 503;
FUNCTION: May function as a transcriptional repressor (By similarity).SUBCELLULAR LOCATION: Nucleus (By similarity).SIMILARITY: Belongs to the Elbow/Noc family.SIMILARITY: Contains 1 C2H2-type zinc finger.SEQUENCE CAUTION: Sequence=BAC03999.1; Type=Erroneous initiation;
Primer design for this transcript
Comparative Toxicogenomics Database (CTD)
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR022129 - Tscrpt_rep_NocA-like
IPR007087 - Znf_C2H2
IPR015880 - Znf_C2H2-like
IPR013087 - Znf_C2H2/integrase_DNA-bd
Pfam Domains: PF12402 - NocA-like zinc-finger protein 1
ModBase Predicted Comparative 3D Structure on Q96F45
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
AK092897 - Homo sapiens cDNA FLJ35578 fis, clone SPLEN2006325, weakly similar to Zinc finger protein nocA.AX747796 - Sequence 1321 from Patent EP1308459.BC011625 - Homo sapiens zinc finger protein 503, mRNA (cDNA clone MGC:10743 IMAGE:4053098), complete cds.BC013011 - Homo sapiens zinc finger protein 503, mRNA (cDNA clone MGC:4159 IMAGE:3604473), complete cds.BC021165 - Homo sapiens zinc finger protein 503, mRNA (cDNA clone MGC:16268 IMAGE:3830632), complete cds.BC007494 - Homo sapiens zinc finger protein 503, mRNA (cDNA clone IMAGE:2967616), complete cds.AK127647 - Homo sapiens cDNA FLJ45745 fis, clone KIDNE2018268, highly similar to Homo sapiens zinc finger protein 503 (ZNF503), mRNA.AK290311 - Homo sapiens cDNA FLJ76083 complete cds, highly similar to Homo sapiens zinc finger protein 503 (ZNF503), mRNA.JD416167 - Sequence 397191 from Patent EP1572962.JD180001 - Sequence 161025 from Patent EP1572962.JD178555 - Sequence 159579 from Patent EP1572962.AK225851 - Homo sapiens mRNA for zinc finger protein 503 variant, clone: FCC125G11.JD215716 - Sequence 196740 from Patent EP1572962.JD340304 - Sequence 321328 from Patent EP1572962.JD343099 - Sequence 324123 from Patent EP1572962.JD460868 - Sequence 441892 from Patent EP1572962.JD460758 - Sequence 441782 from Patent EP1572962.JD217367 - Sequence 198391 from Patent EP1572962.EU446545 - Synthetic construct Homo sapiens clone IMAGE:100070107; IMAGE:100011754; FLH257444.01L zinc finger protein 503 (ZNF503) gene, encodes complete protein.KJ899833 - Synthetic construct Homo sapiens clone ccsbBroadEn_09227 ZNF503 gene, encodes complete protein.KJ906375 - Synthetic construct Homo sapiens clone ccsbBroadEn_16045 ZNF503 gene, encodes complete protein.CU680472 - Synthetic construct Homo sapiens gateway clone IMAGE:100017427 5' read ZNF503 mRNA.LF212561 - JP 2014500723-A/20064: Polycomb-Associated Non-Coding RNAs.MA448138 - JP 2018138019-A/20064: Polycomb-Associated Non-Coding RNAs.
Other Names for This Gene
Alternate Gene Symbols: NM_032772, NP_116161, Q8NAC5, Q96E25, Q96F45, Q96IJ0, ZN503_HUMANUCSC ID: uc001jxg.3RefSeq Accession: NM_032772
Protein: Q96F45
(aka ZN503_HUMAN)
CCDS: CCDS7350.1
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
NM_032772.4
exon count:
2 CDS single in 3' UTR:
no
RNA size:
3198
ORF size:
1941 CDS single in intron:
no
Alignment % ID:
100.00
txCdsPredict score:
4067.50 frame shift in genome:
no
% Coverage:
99.47
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
no
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
0 # strange splices:
0
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Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.