Human Gene ATP13A1 (uc002nnh.4) Description and Page Index
Description: Homo sapiens ATPase type 13A1 (ATP13A1), mRNA.
Transcript (Including UTRs)
Position: hg19 chr19:19,756,010-19,774,503 Size: 18,494 Total Exon Count: 26 Strand: -
Position: hg19 chr19:19,756,231-19,774,475 Size: 18,245 Coding Exon Count: 26
Data last updated: 2013-06-14
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
DESCRIPTION: RecName: Full=Probable cation-transporting ATPase 13A1; EC=3.6.3.-;
CATALYTIC ACTIVITY: ATP + H(2)O = ADP + phosphate. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (By similarity). SIMILARITY: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
Genetic Association Studies of Complex Diseases and Disorders
Genetic Association Database (archive):
ATP13A1 CDC HuGE Published Literature:
Comparative Toxicogenomics Database (CTD)
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR023306 - ATPase_cation_domN
IPR008250 - ATPase_P-typ_ATPase-assoc-dom
IPR023300 - ATPase_P-typ_cyto_domA
IPR023299 - ATPase_P-typ_cyto_domN
IPR001757 - ATPase_P-typ_ion-transptr
IPR018303 - ATPase_P-typ_P_site
IPR006544 - ATPase_P-typ_unknown-pump-sp
IPR023214 - HAD-like_dom
Pfam Domains: PF00122 - E1-E2 ATPase
PF00702 - haloacid dehalogenase-like hydrolase
SCOP Domains: 81653 - Calcium ATPase, transduction domain A
56784 - HAD-like
81660 - Metal cation-transporting ATPase, ATP-binding domain N
ModBase Predicted Comparative 3D Structure on Q9HD20
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
AL834180 - Homo sapiens mRNA; cDNA DKFZp761L1623 (from clone DKFZp761L1623). BC069211 - Homo sapiens ATPase type 13A1, mRNA (cDNA clone IMAGE:4585878), partial cds. BC009302 - Homo sapiens ATPase type 13A1, mRNA (cDNA clone IMAGE:4128479), partial cds. AK172778 - Homo sapiens cDNA FLJ23939 fis, clone HEP01940, highly similar to Cation-transporting ATPase 2 (EC 3.6.3.-). AF288687 - Homo sapiens CGI-152 protein mRNA, complete cds. AK026044 - Homo sapiens cDNA: FLJ22391 fis, clone HRC07832. AK123780 - Homo sapiens cDNA FLJ41786 fis, clone KIDNE2001361, highly similar to Mus musculus catp mRNA for cation-transporting atpase. AK095287 - Homo sapiens cDNA FLJ37968 fis, clone CTONG2009891, highly similar to Probable cation-transporting ATPase 13A1 (EC 3.6.3.-). AK125861 - Homo sapiens cDNA FLJ43873 fis, clone TESTI4008429, highly similar to Probable cation-transporting ATPase 2 (EC 3.6.3.-). AK074798 - Homo sapiens cDNA FLJ90317 fis, clone NT2RP2001514, weakly similar to PROBABLE CALCIUM-TRANSPORTING ATPASE 6 (EC 18.104.22.168). AK074920 - Homo sapiens cDNA FLJ90439 fis, clone NT2RP3000907, weakly similar to PROBABLE CALCIUM-TRANSPORTING ATPASE 6 (EC 22.214.171.124). AK130125 - Homo sapiens cDNA FLJ26615 fis, clone MPB06423, highly similar to Probable cation-transporting ATPase 2 (EC 3.6.3.-). AK074159 - Homo sapiens mRNA for FLJ00232 protein. AB058728 - Homo sapiens mRNA for KIAA1825 protein, partial cds. AK056420 - Homo sapiens cDNA FLJ31858 fis, clone NT2RP7001166, highly similar to Probable cation-transporting ATPase 13A1 (EC 3.6.3.-). JD120935 - Sequence 101959 from Patent EP1572962. JD276566 - Sequence 257590 from Patent EP1572962. JD455970 - Sequence 436994 from Patent EP1572962. JD330188 - Sequence 311212 from Patent EP1572962. JD239706 - Sequence 220730 from Patent EP1572962. KJ902938 - Synthetic construct Homo sapiens clone ccsbBroadEn_12332 ATP13A1 gene, encodes complete protein. BC156250 - Synthetic construct Homo sapiens clone IMAGE:100061633, MGC:190058 ATPase type 13A1 (ATP13A1) mRNA, encodes complete protein. AB385506 - Synthetic construct DNA, clone: pF1KA1825, Homo sapiens ATP13A1 gene for cation-transporting ATPase 13A1, complete cds, without stop codon, in Flexi system. CU679291 - Synthetic construct Homo sapiens gateway clone IMAGE:100018156 5' read ATP13A1 mRNA.
Biochemical and Signaling Pathways
Other Names for This Gene
Alternate Gene Symbols: AT131_HUMAN, ATP13A, B3KPJ2, B3KTA7, CGI-152, KIAA1825, NM_020410, NP_065143, Q9H6C6, Q9HD20 UCSC ID: uc002nnh.4 RefSeq Accession: NM_020410
(aka AT131_HUMAN or ATY2_HUMAN) Q9HD20
Gene Model Information
26 CDS single in 3' UTR:
3615 CDS single in intron:
Alignment % ID:
7277.00 frame shift in genome:
has start codon:
stop codon in genome:
# of Alignments:
has end codon:
# AT/AC introns
end bleed into intron:
0 # strange splices:
for a detailed description of the fields of the table above.
Methods, Credits, and Use Restrictions
for details on how this gene model was made and data restrictions if any.