Human Gene SUPT7L (uc002rli.1) Description and Page Index
Description: Homo sapiens suppressor of Ty 7 (S. cerevisiae)-like (SUPT7L), mRNA. RefSeq Summary (NM_014860): SUPT7L is a protein subunit of the human STAGA complex (SPT3; (MIM 602947)/TAF9 (MIM 600822)/GCN5 (MIM 602301) acetyltransferase complex), which is a chromatin-modifying multiprotein complex (Martinez et al., 2001 [PubMed 11564863]).[supplied by OMIM, Apr 2009]. Transcript (Including UTRs) Position: hg19 chr2:27,873,679-27,886,449 Size: 12,771 Total Exon Count: 6 Strand: - Coding Region Position: hg19 chr2:27,876,352-27,885,059 Size: 8,708 Coding Exon Count: 5
ID:ST65G_HUMAN DESCRIPTION: RecName: Full=STAGA complex 65 subunit gamma; AltName: Full=Adenocarcinoma antigen ART1; AltName: Full=SPTF-associated factor 65 gamma; Short=STAF65gamma; AltName: Full=Suppressor of Ty 7-like; SUBUNIT: Component of the STAGA transcription coactivator-HAT complex, at least composed of SUPT3H, SUPT7L, GCN5L2, TAF5L, TAF6L, TADA3L, TAD1L, TAF10, TAF12 and TAF9. SUBCELLULAR LOCATION: Nucleus. TISSUE SPECIFICITY: Expressed at high levels in adenocarcinomas and gliomas and low in esophageal cancers and malignant hematological disease. Also expressed at high level in the thymus, low in peripheral blood mononuclear cells, and lowest in the stomach, small intestine, and skeletal muscle. PTM: Sumoylated. SEQUENCE CAUTION: Sequence=BAA34484.2; Type=Erroneous initiation;
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on O94864
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.