Human Gene RSRC2 (uc001ucr.3) Description and Page Index
  Description: Homo sapiens arginine/serine-rich coiled-coil 2 (RSRC2), transcript variant 1, mRNA.
Transcript (Including UTRs)
   Position: hg19 chr12:122,989,190-123,011,560 Size: 22,371 Total Exon Count: 10 Strand: -
Coding Region
   Position: hg19 chr12:122,990,074-123,011,400 Size: 21,327 Coding Exon Count: 10 

Page IndexSequence and LinksUniProtKB CommentsCTDGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA Descriptions
Other NamesModel InformationMethods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr12:122,989,190-123,011,560)mRNA (may differ from genome)Protein (434 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaBioGPS
CGAPEnsemblEntrez GeneExonPrimerGeneCardsGeneNetwork
H-INVHGNCHPRDLynxMGIneXtProt
PubMedStanford SOURCETreefamUniProtKB

-  Comments and Description Text from UniProtKB
  ID: RSRC2_HUMAN
DESCRIPTION: RecName: Full=Arginine/serine-rich coiled-coil protein 2;
SIMILARITY: Belongs to the RSRC2 family.
SEQUENCE CAUTION: Sequence=BAB14755.1; Type=Erroneous initiation; Sequence=EAW98327.1; Type=Erroneous gene model prediction;

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 37.14 RPKM in Cells - EBV-transformed lymphocytes
Total median expression: 1288.78 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -61.50160-0.384 Picture PostScript Text
3' UTR -211.90884-0.240 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR026760 - RSRC2

Pfam Domains:
PF15477 - Small acidic protein family

ModBase Predicted Comparative 3D Structure on Q7L4I2
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologGenome BrowserGenome BrowserGenome BrowserGenome BrowserNo ortholog
 Gene Details Gene DetailsGene Details 
 Gene Sorter Gene SorterGene Sorter 
 RGDEnsemblFlyBaseWormBase 
 Protein SequenceProtein SequenceProtein SequenceProtein Sequence 
 AlignmentAlignmentAlignmentAlignment 

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0003723 RNA binding
GO:0005515 protein binding


-  Descriptions from all associated GenBank mRNAs
  BC067773 - Homo sapiens arginine/serine-rich coiled-coil 2, mRNA (cDNA clone MGC:87110 IMAGE:5301415), complete cds.
AB212664 - Homo sapiens mRNA for hypothetical protein, complete cds.
BC008684 - Homo sapiens arginine/serine-rich coiled-coil 2, mRNA (cDNA clone MGC:9742 IMAGE:3853928), complete cds.
BX640711 - Homo sapiens mRNA; cDNA DKFZp686P16221 (from clone DKFZp686P16221).
BX647884 - Homo sapiens mRNA; cDNA DKFZp686E04101 (from clone DKFZp686E04101).
AK023985 - Homo sapiens cDNA FLJ13923 fis, clone Y79AA1000539.
AK056114 - Homo sapiens cDNA FLJ31552 fis, clone NT2RI2001091, weakly similar to SPLICING FACTOR, ARGININE/SERINE-RICH 4.
AK094465 - Homo sapiens cDNA FLJ37146 fis, clone BRACE2024826, weakly similar to H.sapiens PR264 mRNA.
HM245396 - Homo sapiens MIER2-RSRC2 breakpoint junction mRNA sequence.
JD156429 - Sequence 137453 from Patent EP1572962.
AK001883 - Homo sapiens cDNA FLJ11021 fis, clone PLACE1003704, weakly similar to SPLICING FACTOR, ARGININE/SERINE-RICH 4.
JD287254 - Sequence 268278 from Patent EP1572962.
JD499807 - Sequence 480831 from Patent EP1572962.
CU679039 - Synthetic construct Homo sapiens gateway clone IMAGE:100018559 5' read RSRC2 mRNA.
AF161432 - Homo sapiens HSPC314 mRNA, partial cds.
AK056256 - Homo sapiens cDNA FLJ31694 fis, clone NT2RI2005723, weakly similar to SPLICING FACTOR, ARGININE/SERINE-RICH 4.
JD369899 - Sequence 350923 from Patent EP1572962.
JD248288 - Sequence 229312 from Patent EP1572962.
JD394628 - Sequence 375652 from Patent EP1572962.
JD310292 - Sequence 291316 from Patent EP1572962.
JD241550 - Sequence 222574 from Patent EP1572962.
JD332079 - Sequence 313103 from Patent EP1572962.
JD138237 - Sequence 119261 from Patent EP1572962.
JD139363 - Sequence 120387 from Patent EP1572962.
JD108439 - Sequence 89463 from Patent EP1572962.
JD257434 - Sequence 238458 from Patent EP1572962.
JD546165 - Sequence 527189 from Patent EP1572962.
JD263352 - Sequence 244376 from Patent EP1572962.
JD238737 - Sequence 219761 from Patent EP1572962.
JD168859 - Sequence 149883 from Patent EP1572962.
JD139352 - Sequence 120376 from Patent EP1572962.
JD043643 - Sequence 24667 from Patent EP1572962.
JD504877 - Sequence 485901 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: NM_023012, NP_075388, Q6N040, Q6NW16, Q7L4I2, Q9H864, RSRC2_HUMAN
UCSC ID: uc001ucr.3
RefSeq Accession: NM_023012
Protein: Q7L4I2 (aka RSRC2_HUMAN)
CCDS: CCDS31920.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_023012.5
exon count: 10CDS single in 3' UTR: no RNA size: 2349
ORF size: 1305CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 2303.00frame shift in genome: no % Coverage: 100.00
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.