Human Gene C4orf3 (uc021xrf.1) Description and Page Index
  Description: Homo sapiens chromosome 4 open reading frame 3 (C4orf3), transcript variant 1, mRNA.
Transcript (Including UTRs)
   Position: hg19 chr4:120,217,574-120,225,600 Size: 8,027 Total Exon Count: 3 Strand: -
Coding Region
   Position: hg19 chr4:120,219,934-120,225,600 Size: 5,667 Coding Exon Count: 3 

Page IndexSequence and LinksMalaCardsCTDGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther Names
Model InformationMethods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr4:120,217,574-120,225,600)mRNA (may differ from genome)Protein (199 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaBioGPS
CGAPEnsemblEntrez GeneExonPrimerGeneCardsH-INV
HGNCLynxMGIPubMedStanford SOURCETreefam
UniProtKB

-  MalaCards Disease Associations
  MalaCards Gene Search: C4orf3
Diseases sorted by gene-association score: hepatitis c virus (2)

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 101.29 RPKM in Esophagus - Mucosa
Total median expression: 2959.59 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
3' UTR -691.752360-0.293 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  ModBase Predicted Comparative 3D Structure on Q8WVX3-2
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGD    
 Protein Sequence    
 Alignment    

-  Descriptions from all associated GenBank mRNAs
  KJ904277 - Synthetic construct Homo sapiens clone ccsbBroadEn_13671 C4orf3 gene, encodes complete protein.
JD204029 - Sequence 185053 from Patent EP1572962.
AK025703 - Homo sapiens cDNA: FLJ22050 fis, clone HEP09454.
JD557783 - Sequence 538807 from Patent EP1572962.
JD430677 - Sequence 411701 from Patent EP1572962.
JD083230 - Sequence 64254 from Patent EP1572962.
AK024537 - Homo sapiens cDNA: FLJ20884 fis, clone ADKA03239.
BC017399 - Homo sapiens chromosome 4 open reading frame 3, mRNA (cDNA clone MGC:24558 IMAGE:4108498), complete cds.
AF075061 - Homo sapiens full length insert cDNA YP07G10.
LF353211 - JP 2014500723-A/160714: Polycomb-Associated Non-Coding RNAs.
HQ448211 - Synthetic construct Homo sapiens clone IMAGE:100071610; CCSB007511_01 HCV F-transactivated protein 1 (LOC401152) gene, encodes complete protein.
AY605045 - Homo sapiens HCV F-transactivated protein 1 mRNA, complete cds.
LF353210 - JP 2014500723-A/160713: Polycomb-Associated Non-Coding RNAs.
LF353209 - JP 2014500723-A/160712: Polycomb-Associated Non-Coding RNAs.
MA588788 - JP 2018138019-A/160714: Polycomb-Associated Non-Coding RNAs.
MA588787 - JP 2018138019-A/160713: Polycomb-Associated Non-Coding RNAs.
MA588786 - JP 2018138019-A/160712: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: NM_001170330, NP_001163801, Q8WVX3-2
UCSC ID: uc021xrf.1
RefSeq Accession: NM_001170330
Protein: Q8WVX3-2, splice isoform of Q8WVX3 CCDS: CCDS54798.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_001170330.1
exon count: 3CDS single in 3' UTR: no RNA size: 2975
ORF size: 600CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 912.00frame shift in genome: no % Coverage: 99.50
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.