Alcoholism Andrew C Heath et al. Biological psychiatry 2011, A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications., Biological psychiatry.
[PubMed 21529783]
We conclude that 1) meta-analyses of consumption data may contribute usefully to gene discovery; 2) translation of human alcoholism GWAS results to drug discovery or clinically useful prediction of risk will be challenging; and 3) through accumulation across studies, GWAS data may become valuable for improved genetic risk differentiation in research in biological psychiatry (e.g., prospective high-risk or resilience studies).
Bipolar Disorder M T M Lee et al. Molecular psychiatry 2011, Genome-wide association study of bipolar I disorder in the Han Chinese population., Molecular psychiatry.
[PubMed 20386566]
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
ModBase Predicted Comparative 3D Structure on Q32M92
Front
Top
Side
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse
Rat
Zebrafish
D. melanogaster
C. elegans
S. cerevisiae
No ortholog
No ortholog
No ortholog
No ortholog
No ortholog
No ortholog
Descriptions from all associated GenBank mRNAs
LP895987 - Sequence 851 from Patent EP3253886. AK057393 - Homo sapiens cDNA FLJ32831 fis, clone TESTI2003193. JD192088 - Sequence 173112 from Patent EP1572962. JD071851 - Sequence 52875 from Patent EP1572962. JD466269 - Sequence 447293 from Patent EP1572962. JD439419 - Sequence 420443 from Patent EP1572962. JD232916 - Sequence 213940 from Patent EP1572962. JD563983 - Sequence 545007 from Patent EP1572962. JD181567 - Sequence 162591 from Patent EP1572962. BC109252 - Homo sapiens chromosome 15 open reading frame 32, mRNA (cDNA clone MGC:129836 IMAGE:40023840), complete cds. BC109253 - Homo sapiens chromosome 15 open reading frame 32, mRNA (cDNA clone MGC:129837 IMAGE:40023844), complete cds. JD422494 - Sequence 403518 from Patent EP1572962. JD044992 - Sequence 26016 from Patent EP1572962. JD112931 - Sequence 93955 from Patent EP1572962. KJ903836 - Synthetic construct Homo sapiens clone ccsbBroadEn_13230 C15orf32 gene, encodes complete protein. JD036725 - Sequence 17749 from Patent EP1572962. JD284322 - Sequence 265346 from Patent EP1572962. JD245310 - Sequence 226334 from Patent EP1572962. JD485508 - Sequence 466532 from Patent EP1572962. JD448396 - Sequence 429420 from Patent EP1572962. JD364735 - Sequence 345759 from Patent EP1572962. JD327413 - Sequence 308437 from Patent EP1572962. JD321435 - Sequence 302459 from Patent EP1572962. JD292859 - Sequence 273883 from Patent EP1572962. JD327540 - Sequence 308564 from Patent EP1572962.