Human Gene TP53I11 (uc001myk.3)
Description: Homo sapiens tumor protein p53 inducible protein 11 (TP53I11), transcript variant 6, mRNA.
Transcript (Including UTRs)
Position: hg19 chr11:44,953,899-44,972,608 Size: 18,710 Total Exon Count: 7 Strand: -
Coding Region
Position: hg19 chr11:44,956,435-44,959,886 Size: 3,452 Coding Exon Count: 6
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: P5I11_HUMAN
DESCRIPTION: RecName: Full=Tumor protein p53-inducible protein 11; AltName: Full=p53-induced gene 11 protein;
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (Potential).INDUCTION: By p53/TP53.SEQUENCE CAUTION: Sequence=AAC39533.1; Type=Miscellaneous discrepancy; Note=Localized in an untranslated region: wrong choice of CDS;
Primer design for this transcript
Genetic Association Studies of Complex Diseases and Disorders
Comparative Toxicogenomics Database (CTD)
Common Gene Haplotype Alleles
Press "+" in the title bar above to open this section.
RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
Press "+" in the title bar above to open this section.
mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
Pfam Domains: PF14936 - Tumour protein p53-inducible protein 11
ModBase Predicted Comparative 3D Structure on O14683
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Biological Process: GO:0008285 negative regulation of cell proliferation
Cellular Component: GO:0016020 membrane
GO:0016021 integral component of membrane
Descriptions from all associated GenBank mRNAs
AK026607 - Homo sapiens cDNA: FLJ22954 fis, clone KAT09813, highly similar to AF010315 Homo sapiens Pig11 (PIG11) mRNA.U79302 - Human clone 23855 mRNA, partial cds.AK056379 - Homo sapiens cDNA FLJ31817 fis, clone NT2RP6000008, moderately similar to Homo sapiens Pig11 (PIG11) mRNA.AK054815 - Homo sapiens cDNA FLJ30253 fis, clone BRACE2002431, moderately similar to P53-INDUCED PROTEIN 11.AK096176 - Homo sapiens cDNA FLJ38857 fis, clone MESAN2011597.BC045666 - Homo sapiens tumor protein p53 inducible protein 11, mRNA (cDNA clone MGC:44491 IMAGE:5298525), complete cds.BC071606 - Homo sapiens tumor protein p53 inducible protein 11, mRNA (cDNA clone IMAGE:4822518), partial cds.AK292837 - Homo sapiens cDNA FLJ76159 complete cds, highly similar to Homo sapiens tumor protein p53 inducible protein 11 (TP53I11), mRNA.AB587371 - Synthetic construct DNA, clone: pF1KB4576, Homo sapiens TP53I11 gene for tumor protein p53 inducible protein 11, without stop codon, in Flexi system.AF010315 - Homo sapiens Pig11 (PIG11) mRNA, complete cds.BC000443 - Homo sapiens tumor protein p53 inducible protein 11, mRNA (cDNA clone IMAGE:2820767).BC003010 - Homo sapiens tumor protein p53 inducible protein 11, mRNA (cDNA clone IMAGE:2820767).BC065557 - Homo sapiens tumor protein p53 inducible protein 11, mRNA (cDNA clone IMAGE:6138729).JD094313 - Sequence 75337 from Patent EP1572962.JD252891 - Sequence 233915 from Patent EP1572962.JD124023 - Sequence 105047 from Patent EP1572962.JD406377 - Sequence 387401 from Patent EP1572962.JD497029 - Sequence 478053 from Patent EP1572962.JD051909 - Sequence 32933 from Patent EP1572962.JD481818 - Sequence 462842 from Patent EP1572962.JD080562 - Sequence 61586 from Patent EP1572962.JD466103 - Sequence 447127 from Patent EP1572962.JD272800 - Sequence 253824 from Patent EP1572962.KJ901991 - Synthetic construct Homo sapiens clone ccsbBroadEn_11385 TP53I11 gene, encodes complete protein.CU688072 - Synthetic construct Homo sapiens gateway clone IMAGE:100021556 5' read TP53I11 mRNA.JD126254 - Sequence 107278 from Patent EP1572962.JD054012 - Sequence 35036 from Patent EP1572962.JD056204 - Sequence 37228 from Patent EP1572962.JD162532 - Sequence 143556 from Patent EP1572962.JD054012 - Sequence 35036 from Patent EP1572962.JD056204 - Sequence 37228 from Patent EP1572962.JD117409 - Sequence 98433 from Patent EP1572962.JD209184 - Sequence 190208 from Patent EP1572962.JD137618 - Sequence 118642 from Patent EP1572962.JD381433 - Sequence 362457 from Patent EP1572962.JD060703 - Sequence 41727 from Patent EP1572962.JD280115 - Sequence 261139 from Patent EP1572962.JD189042 - Sequence 170066 from Patent EP1572962.JD404737 - Sequence 385761 from Patent EP1572962.JD050395 - Sequence 31419 from Patent EP1572962.JD097236 - Sequence 78260 from Patent EP1572962.JD097154 - Sequence 78178 from Patent EP1572962.JD097120 - Sequence 78144 from Patent EP1572962.JD526784 - Sequence 507808 from Patent EP1572962.JD077852 - Sequence 58876 from Patent EP1572962.JD311285 - Sequence 292309 from Patent EP1572962.JD156090 - Sequence 137114 from Patent EP1572962.JD392785 - Sequence 373809 from Patent EP1572962.JD399636 - Sequence 380660 from Patent EP1572962.JD399637 - Sequence 380661 from Patent EP1572962.JD399639 - Sequence 380663 from Patent EP1572962.JD136526 - Sequence 117550 from Patent EP1572962.JD383612 - Sequence 364636 from Patent EP1572962.JD399652 - Sequence 380676 from Patent EP1572962.JD394964 - Sequence 375988 from Patent EP1572962.JD394953 - Sequence 375977 from Patent EP1572962.JD056102 - Sequence 37126 from Patent EP1572962.JD204994 - Sequence 186018 from Patent EP1572962.
Other Names for This Gene
Alternate Gene Symbols: NM_006034, NP_006025, O14683, P5I11_HUMAN, PIG11, Q3ZCS0UCSC ID: uc001myk.3RefSeq Accession: NM_006034
Protein: O14683
(aka P5I11_HUMAN)
CCDS: CCDS7911.1
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
NM_006034.3
exon count:
7 CDS single in 3' UTR:
no
RNA size:
3518
ORF size:
570 CDS single in intron:
no
Alignment % ID:
99.97
txCdsPredict score:
1200.00 frame shift in genome:
no
% Coverage:
100.00
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
no
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
0 # strange splices:
0
Click here
for a detailed description of the fields of the table above.
Methods, Credits, and Use Restrictions
Click here
for details on how this gene model was made and data restrictions if any.