The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q86Y91-3
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
DQ595941 - Homo sapiens piRNA piR-62053, complete sequence. BC048263 - Homo sapiens hypothetical protein LOC146909, mRNA (cDNA clone IMAGE:4418755), partial cds. BC067365 - Homo sapiens kinesin family member 18B, mRNA (cDNA clone IMAGE:4587138), partial cds. BC044933 - Homo sapiens kinesin family member 18B, mRNA (cDNA clone IMAGE:4540326), partial cds. JD545858 - Sequence 526882 from Patent EP1572962. JD178308 - Sequence 159332 from Patent EP1572962. JD318087 - Sequence 299111 from Patent EP1572962. JD275836 - Sequence 256860 from Patent EP1572962. JD474290 - Sequence 455314 from Patent EP1572962. JD125376 - Sequence 106400 from Patent EP1572962. JD119379 - Sequence 100403 from Patent EP1572962. JD196972 - Sequence 177996 from Patent EP1572962. JD116533 - Sequence 97557 from Patent EP1572962. JD285474 - Sequence 266498 from Patent EP1572962. JD272333 - Sequence 253357 from Patent EP1572962. JD064306 - Sequence 45330 from Patent EP1572962. JD237803 - Sequence 218827 from Patent EP1572962. JD285420 - Sequence 266444 from Patent EP1572962. JD285419 - Sequence 266443 from Patent EP1572962. JD072212 - Sequence 53236 from Patent EP1572962. JD499753 - Sequence 480777 from Patent EP1572962. JD426771 - Sequence 407795 from Patent EP1572962. JD489177 - Sequence 470201 from Patent EP1572962. JD374550 - Sequence 355574 from Patent EP1572962. JD489176 - Sequence 470200 from Patent EP1572962. JD409296 - Sequence 390320 from Patent EP1572962. JD321969 - Sequence 302993 from Patent EP1572962. JD515264 - Sequence 496288 from Patent EP1572962. JD119360 - Sequence 100384 from Patent EP1572962. JD301281 - Sequence 282305 from Patent EP1572962. JD288702 - Sequence 269726 from Patent EP1572962. JD160624 - Sequence 141648 from Patent EP1572962. JD273155 - Sequence 254179 from Patent EP1572962. JD173056 - Sequence 154080 from Patent EP1572962. JD203446 - Sequence 184470 from Patent EP1572962. BC136590 - Homo sapiens kinesin family member 18B, mRNA (cDNA clone MGC:168203 IMAGE:9020580), complete cds. BC144271 - Homo sapiens kinesin family member 18B, mRNA (cDNA clone MGC:177808 IMAGE:9052791), complete cds. JD220599 - Sequence 201623 from Patent EP1572962. JD111120 - Sequence 92144 from Patent EP1572962. GU808359 - Homo sapiens cell-line HeLa KIF18B mRNA, complete cds. JD065058 - Sequence 46082 from Patent EP1572962.
Biochemical and Signaling Pathways
Reactome (by CSHL, EBI, and GO)
Protein Q86Y91 (Reactome details) participates in the following event(s):
R-HSA-983266 Kinesins bind microtubules R-HSA-6811426 Retrograde COPI vesicles bind kinesin and microtubules R-HSA-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs R-HSA-983189 Kinesins R-HSA-6811434 COPI-dependent Golgi-to-ER retrograde traffic R-HSA-983231 Factors involved in megakaryocyte development and platelet production R-HSA-8856688 Golgi-to-ER retrograde transport R-HSA-109582 Hemostasis R-HSA-6811442 Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-199991 Membrane Trafficking R-HSA-5653656 Vesicle-mediated transport