Human Gene PCNX3 (uc001oey.2)
  Description: Homo sapiens pecanex-like 3 (Drosophila) (PCNX3), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr11:65,383,783-65,404,910 Size: 21,128 Total Exon Count: 35 Strand: +
Coding Region
   Position: hg19 chr11:65,383,783-65,404,449 Size: 20,667 Coding Exon Count: 35 

Page IndexSequence and LinksUniProtKB CommentsPrimersGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA Descriptions
Other NamesModel InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr11:65,383,783-65,404,910)mRNA (may differ from genome)Protein (2034 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsGeneNetwork
H-INVHPRDLynxMGIneXtProtOMIM
PubMedTreefamUniProtKBBioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: PCX3_HUMAN
DESCRIPTION: RecName: Full=Pecanex-like protein 3;
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (Potential).
SIMILARITY: Belongs to the pecanex family.
SEQUENCE CAUTION: Sequence=BAB15353.1; Type=Erroneous initiation;

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 19.44 RPKM in Testis
Total median expression: 462.80 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
3' UTR -158.83461-0.345 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR007735 - Pecanex

Pfam Domains:
PF05041 - Pecanex protein (C-terminus)

ModBase Predicted Comparative 3D Structure on Q9H6A9
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologGenome BrowserGenome BrowserNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGDEnsembl   
 Protein SequenceProtein Sequence   
 AlignmentAlignment   

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Cellular Component:
GO:0016020 membrane
GO:0016021 integral component of membrane


-  Descriptions from all associated GenBank mRNAs
  AK026080 - Homo sapiens cDNA: FLJ22427 fis, clone HRC09013.
AK308625 - Homo sapiens cDNA, FLJ98666.
BX640978 - Homo sapiens mRNA; cDNA DKFZp686M14190 (from clone DKFZp686M14190).
JD322839 - Sequence 303863 from Patent EP1572962.
JD344435 - Sequence 325459 from Patent EP1572962.
JD394274 - Sequence 375298 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: NM_032223, NP_115599, PCNXL3, PCX3_HUMAN, Q6MZN8, Q9H6A9
UCSC ID: uc001oey.2
RefSeq Accession: NM_032223
Protein: Q9H6A9 (aka PCX3_HUMAN)
CCDS: CCDS44650.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_032223.2
exon count: 35CDS single in 3' UTR: no RNA size: 6584
ORF size: 6105CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 9303.00frame shift in genome: no % Coverage: 99.73
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.