Human Gene MTFR1L (uc001bkq.4)
Description: Homo sapiens mitochondrial fission regulator 1-like (MTFR1L), nuclear gene encoding mitochondrial protein, transcript variant 2, mRNA.
Transcript (Including UTRs)
Position: hg19 chr1:26,146,397-26,159,433 Size: 13,037 Total Exon Count: 7 Strand: +
Coding Region
Position: hg19 chr1:26,149,596-26,158,517 Size: 8,922 Coding Exon Count: 6
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: FA54B_HUMAN
DESCRIPTION: RecName: Full=Protein FAM54B;
SIMILARITY: Belongs to the MTFR1/FAM54 family.SEQUENCE CAUTION: Sequence=AAQ13638.1; Type=Frameshift; Positions=7, 49;
Primer design for this transcript
Comparative Toxicogenomics Database (CTD)
The following chemicals interact with this gene
Common Gene Haplotype Alleles
Press "+" in the title bar above to open this section.
RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
Press "+" in the title bar above to open this section.
mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR007972 - Mtfr1
Pfam Domains: PF05308 - Mitochondrial fission regulator
ModBase Predicted Comparative 3D Structure on Q9H019
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
BX647921 - Homo sapiens mRNA; cDNA DKFZp686M0519 (from clone DKFZp686M0519).AK314297 - Homo sapiens cDNA, FLJ95054.AB075880 - Homo sapiens mRNA for putative protein product of HYST1888, complete cds.AK299221 - Homo sapiens cDNA FLJ55391 complete cds.AF173891 - Homo sapiens MSTP116 (MST116) mRNA, complete cds.AL512766 - Homo sapiens mRNA; cDNA DKFZp564M0163 (from clone DKFZp564M0163).BC017175 - Homo sapiens family with sequence similarity 54, member B, mRNA (cDNA clone MGC:1164 IMAGE:3162883), complete cds.AY007100 - Homo sapiens clone TCCCIA00201 mRNA sequence.AK056721 - Homo sapiens cDNA FLJ32159 fis, clone PLACE6000263.JD044526 - Sequence 25550 from Patent EP1572962.AK290744 - Homo sapiens cDNA FLJ77646 complete cds.JD314258 - Sequence 295282 from Patent EP1572962.AB528297 - Synthetic construct DNA, clone: pF1KE0158, Homo sapiens FAM54B gene for family with sequence similarity 54, member B, without stop codon, in Flexi system.KJ894317 - Synthetic construct Homo sapiens clone ccsbBroadEn_03711 FAM54B gene, encodes complete protein.KU178723 - Homo sapiens family with sequence similarity 54 member B isoform 1 (FAM54B) mRNA, partial cds.KU178724 - Homo sapiens family with sequence similarity 54 member B isoform 2 (FAM54B) mRNA, complete cds, alternatively spliced.AM393476 - Synthetic construct Homo sapiens clone IMAGE:100002006 for hypothetical protein (FAM54B gene).AK127164 - Homo sapiens cDNA FLJ45228 fis, clone BRCAN2020880.AK302324 - Homo sapiens cDNA FLJ52801 complete cds, highly similar to Nucleolar protein 4.JD155435 - Sequence 136459 from Patent EP1572962.JD515788 - Sequence 496812 from Patent EP1572962.JD402421 - Sequence 383445 from Patent EP1572962.JD521251 - Sequence 502275 from Patent EP1572962.JD237263 - Sequence 218287 from Patent EP1572962.JD341113 - Sequence 322137 from Patent EP1572962.JD436356 - Sequence 417380 from Patent EP1572962.JD166034 - Sequence 147058 from Patent EP1572962.JD062938 - Sequence 43962 from Patent EP1572962.DQ595805 - Homo sapiens piRNA piR-61917, complete sequence.DQ601349 - Homo sapiens piRNA piR-39415, complete sequence.JD521698 - Sequence 502722 from Patent EP1572962.JD403049 - Sequence 384073 from Patent EP1572962.JD551148 - Sequence 532172 from Patent EP1572962.JD492848 - Sequence 473872 from Patent EP1572962.JD114467 - Sequence 95491 from Patent EP1572962.JD270400 - Sequence 251424 from Patent EP1572962.JD387170 - Sequence 368194 from Patent EP1572962.JD446455 - Sequence 427479 from Patent EP1572962.JD169005 - Sequence 150029 from Patent EP1572962.JD383272 - Sequence 364296 from Patent EP1572962.JD052892 - Sequence 33916 from Patent EP1572962.JD563793 - Sequence 544817 from Patent EP1572962.JD352206 - Sequence 333230 from Patent EP1572962.JD500129 - Sequence 481153 from Patent EP1572962.JD237087 - Sequence 218111 from Patent EP1572962.JD192134 - Sequence 173158 from Patent EP1572962.JD225483 - Sequence 206507 from Patent EP1572962.JD073421 - Sequence 54445 from Patent EP1572962.JD434727 - Sequence 415751 from Patent EP1572962.JD485257 - Sequence 466281 from Patent EP1572962.JD554206 - Sequence 535230 from Patent EP1572962.
Other Names for This Gene
Alternate Gene Symbols: A6NCB4, B7WNV5, D3DPJ4, FA54B_HUMAN, FAM54B, HYST1888, MSTP116, NM_001099625, NP_062457, Q63HP1, Q7Z2S7, Q9H019, Q9NUI7UCSC ID: uc001bkq.4RefSeq Accession: NM_001099625
Protein: Q9H019
(aka FA54B_HUMAN)
CCDS: CCDS41284.1
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
NM_001099625.1
exon count:
7 CDS single in 3' UTR:
no
RNA size:
2022
ORF size:
879 CDS single in intron:
no
Alignment % ID:
100.00
txCdsPredict score:
1846.00 frame shift in genome:
no
% Coverage:
99.16
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
no
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
0 # strange splices:
0
Click here
for a detailed description of the fields of the table above.
Methods, Credits, and Use Restrictions
Click here
for details on how this gene model was made and data restrictions if any.