Human Gene ZDHHC16 (uc001knk.3)
Description: Homo sapiens zinc finger, DHHC-type containing 16 (ZDHHC16), transcript variant 1, mRNA.
Transcript (Including UTRs)
Position: hg19 chr10:99,205,930-99,217,127 Size: 11,198 Total Exon Count: 11 Strand: +
Coding Region
Position: hg19 chr10:99,211,433-99,216,648 Size: 5,216 Coding Exon Count: 10
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: ZDH16_HUMAN
DESCRIPTION: RecName: Full=Probable palmitoyltransferase ZDHHC16; EC=2.3.1.-; AltName: Full=Zinc finger DHHC domain-containing protein 16; Short=DHHC-16;
FUNCTION: May be involved in apoptosis regulation (By similarity).CATALYTIC ACTIVITY: Palmitoyl-CoA + protein-cysteine = S-palmitoyl protein + CoA.SUBUNIT: Interacts with ABL1 (By similarity).SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity).DOMAIN: The DHHC domain is required for palmitoyltransferase activity (By similarity).SIMILARITY: Belongs to the DHHC palmitoyltransferase family.SIMILARITY: Contains 1 DHHC-type zinc finger.
Primer design for this transcript
Genetic Association Studies of Complex Diseases and Disorders
Genetic Association Database (archive): ZDHHC16
CDC HuGE Published Literature: ZDHHC16
Comparative Toxicogenomics Database (CTD)
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR001594 - Znf_DHHC_palmitoyltrfase
Pfam Domains: PF01529 - DHHC palmitoyltransferase
ModBase Predicted Comparative 3D Structure on Q969W1
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
BC008074 - Homo sapiens zinc finger, DHHC-type containing 16, mRNA (cDNA clone MGC:2911 IMAGE:3029918), complete cds.BC012830 - Homo sapiens zinc finger, DHHC-type containing 16, mRNA (cDNA clone MGC:4571 IMAGE:3029918), complete cds.AK297962 - Homo sapiens cDNA FLJ58319 complete cds, highly similar to Probable palmitoyltransferase ZDHHC16 (EC 2.3.1.-).AK074427 - Homo sapiens cDNA FLJ23847 fis, clone KAT10287, highly similar to Mus musculus Abl-philin 2 mRNA.BC011749 - Homo sapiens zinc finger, DHHC-type containing 16, mRNA (cDNA clone MGC:19657 IMAGE:3140177), complete cds.BC050652 - Homo sapiens zinc finger, DHHC-type containing 16, mRNA (cDNA clone IMAGE:5241351), with apparent retained intron.AF258563 - Homo sapiens PP3774 mRNA, complete cds.BC033157 - Homo sapiens zinc finger, DHHC-type containing 16, mRNA (cDNA clone MGC:45785 IMAGE:4309312), complete cds.BC004535 - Homo sapiens zinc finger, DHHC-type containing 16, mRNA (cDNA clone MGC:2993 IMAGE:3160750), complete cds.AY359080 - Homo sapiens clone DNA108688 ZDHHC16 (UNQ2570) mRNA, complete cds.JD406007 - Sequence 387031 from Patent EP1572962.JD458155 - Sequence 439179 from Patent EP1572962.JD128201 - Sequence 109225 from Patent EP1572962.AJ294945 - Homo sapiens mRNA for hypothetical protein.AB209272 - Homo sapiens mRNA for Abl-philin 2 isoform 3 variant protein.AB464420 - Synthetic construct DNA, clone: pF1KB8158, Homo sapiens ZDHHC16 gene for zinc finger, DHHC-type containing protein 16, without stop codon, in Flexi system.CU675921 - Synthetic construct Homo sapiens gateway clone IMAGE:100019148 5' read ZDHHC16 mRNA.CU678754 - Synthetic construct Homo sapiens gateway clone IMAGE:100016994 5' read ZDHHC16 mRNA.HQ447851 - Synthetic construct Homo sapiens clone IMAGE:100071195; CCSB004483_01 zinc finger, DHHC-type containing 16 (ZDHHC16) gene, encodes complete protein.KJ894964 - Synthetic construct Homo sapiens clone ccsbBroadEn_04358 ZDHHC16 gene, encodes complete protein.KJ899782 - Synthetic construct Homo sapiens clone ccsbBroadEn_09176 ZDHHC16 gene, encodes complete protein.JD138501 - Sequence 119525 from Patent EP1572962.JD250462 - Sequence 231486 from Patent EP1572962.JD261220 - Sequence 242244 from Patent EP1572962.JD050071 - Sequence 31095 from Patent EP1572962.JD328385 - Sequence 309409 from Patent EP1572962.JD074795 - Sequence 55819 from Patent EP1572962.JD197014 - Sequence 178038 from Patent EP1572962.JD203382 - Sequence 184406 from Patent EP1572962.JD420567 - Sequence 401591 from Patent EP1572962.JD326683 - Sequence 307707 from Patent EP1572962.
Other Names for This Gene
Alternate Gene Symbols: D3DR52, D3DR53, D3DR54, NM_032327, NP_932163, Q5JTG7, Q5JTH0, Q8N4Z6, Q8WY84, Q969W1, Q9BSV3, UNQ2570/PRO6258, ZDH16_HUMANUCSC ID: uc001knk.3RefSeq Accession: NM_032327
Protein: Q969W1
(aka ZDH16_HUMAN or ZDHG_HUMAN)
CCDS: CCDS7460.1 , CCDS7461.1
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
NM_032327.2
exon count:
11 CDS single in 3' UTR:
no
RNA size:
1816
ORF size:
1134 CDS single in intron:
no
Alignment % ID:
100.00
txCdsPredict score:
2356.00 frame shift in genome:
no
% Coverage:
99.06
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
no
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
0 # strange splices:
0
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Methods, Credits, and Use Restrictions
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