Human Gene GPN2 (uc001bnd.1)
Description: Homo sapiens GPN-loop GTPase 2 (GPN2), mRNA.
Transcript (Including UTRs)
Position: hg19 chr1:27,205,873-27,216,869 Size: 10,997 Total Exon Count: 5 Strand: -
Coding Region
Position: hg19 chr1:27,206,168-27,216,587 Size: 10,420 Coding Exon Count: 5
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: GPN2_HUMAN
DESCRIPTION: RecName: Full=GPN-loop GTPase 2; AltName: Full=ATP-binding domain 1 family member B;
SIMILARITY: Belongs to the GPN-loop GTPase family.
Primer design for this transcript
Comparative Toxicogenomics Database (CTD)
The following chemicals interact with this gene
Common Gene Haplotype Alleles
Press "+" in the title bar above to open this section.
RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
Press "+" in the title bar above to open this section.
mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR004130 - Uncharacterised_ATP-bd
Pfam Domains: PF03029 - Conserved hypothetical ATP binding protein
SCOP Domains: 52540 - P-loop containing nucleoside triphosphate hydrolases
ModBase Predicted Comparative 3D Structure on Q9H9Y4
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
AY358864 - Homo sapiens clone DNA145690 AGAA5828 (UNQ5828) mRNA, complete cds.LF206657 - JP 2014500723-A/14160: Polycomb-Associated Non-Coding RNAs.BC007815 - Homo sapiens GPN-loop GTPase 2, mRNA (cDNA clone MGC:14380 IMAGE:4299794), complete cds.BC008634 - Homo sapiens GPN-loop GTPase 2, mRNA (cDNA clone MGC:9656 IMAGE:3463813), complete cds.BC020272 - Homo sapiens GPN-loop GTPase 2, mRNA (cDNA clone IMAGE:3544026).AK022535 - Homo sapiens cDNA FLJ12473 fis, clone NT2RM1000924, weakly similar to HYPOTHETICAL 39.7 KD PROTEIN C34E10.2 IN CHROMOSOME III.AK001211 - Homo sapiens cDNA FLJ10349 fis, clone NT2RM2001100.JD396731 - Sequence 377755 from Patent EP1572962.JD287931 - Sequence 268955 from Patent EP1572962.JD465984 - Sequence 447008 from Patent EP1572962.JD218405 - Sequence 199429 from Patent EP1572962.JD542194 - Sequence 523218 from Patent EP1572962.AY364261 - Homo sapiens clone peg2039 hypothetical protein (FLJ10349) mRNA, complete cds.JD444567 - Sequence 425591 from Patent EP1572962.JD450394 - Sequence 431418 from Patent EP1572962.JD253929 - Sequence 234953 from Patent EP1572962.JD267884 - Sequence 248908 from Patent EP1572962.JD060719 - Sequence 41743 from Patent EP1572962.JD535648 - Sequence 516672 from Patent EP1572962.JD310093 - Sequence 291117 from Patent EP1572962.HQ448689 - Synthetic construct Homo sapiens clone IMAGE:100072132; CCSB002785_02 ATP binding domain 1 family, member B (GPN2) gene, encodes complete protein.KJ899010 - Synthetic construct Homo sapiens clone ccsbBroadEn_08404 GPN2 gene, encodes complete protein.KJ899011 - Synthetic construct Homo sapiens clone ccsbBroadEn_08405 GPN2 gene, encodes complete protein.CU675813 - Synthetic construct Homo sapiens gateway clone IMAGE:100018832 5' read ATPBD1B mRNA.LF356961 - JP 2014500723-A/164464: Polycomb-Associated Non-Coding RNAs.JD024466 - Sequence 5490 from Patent EP1572962.JD036134 - Sequence 17158 from Patent EP1572962.JD025062 - Sequence 6086 from Patent EP1572962.JD393712 - Sequence 374736 from Patent EP1572962.JD032017 - Sequence 13041 from Patent EP1572962.JD228277 - Sequence 209301 from Patent EP1572962.MA442234 - JP 2018138019-A/14160: Polycomb-Associated Non-Coding RNAs.MA592538 - JP 2018138019-A/164464: Polycomb-Associated Non-Coding RNAs.
Other Names for This Gene
Alternate Gene Symbols: ATPBD1B, GPN2_HUMAN, NM_018066, NP_060536, Q96HG4, Q9H9Y4, Q9NUE1, Q9NW30, UNQ5828/PRO19647UCSC ID: uc001bnd.1RefSeq Accession: NM_018066
Protein: Q9H9Y4
(aka GPN2_HUMAN)
CCDS: CCDS289.1
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
NM_018066.3
exon count:
5 CDS single in 3' UTR:
no
RNA size:
1510
ORF size:
933 CDS single in intron:
no
Alignment % ID:
100.00
txCdsPredict score:
2066.00 frame shift in genome:
no
% Coverage:
100.00
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
no
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
0 # strange splices:
0
Click here
for a detailed description of the fields of the table above.
Methods, Credits, and Use Restrictions
Click here
for details on how this gene model was made and data restrictions if any.