Human Gene VCPKMT (uc001wxo.1)
Description: Homo sapiens methyltransferase like 21D (VCPKMT), transcript variant 1, mRNA.
Transcript (Including UTRs)
Position: hg19 chr14:50,575,350-50,583,297 Size: 7,948 Total Exon Count: 6 Strand: -
Coding Region
Position: hg19 chr14:50,576,417-50,583,270 Size: 6,854 Coding Exon Count: 6
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: MT21D_HUMAN
DESCRIPTION: RecName: Full=Methyltransferase-like protein 21D; EC=2.1.1.-;
FUNCTION: Probable methyltransferase (By similarity).SIMILARITY: Belongs to the methyltransferase superfamily. METTL21 family.SEQUENCE CAUTION: Sequence=CAD62329.1; Type=Erroneous initiation;
Primer design for this transcript
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR019410 - Nicotinamide_N-MeTfrase-like
Pfam Domains: PF10294 - Lysine methyltransferase
SCOP Domains: 53335 - S-adenosyl-L-methionine-dependent methyltransferases
ModBase Predicted Comparative 3D Structure on Q9H867
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
BC027585 - Homo sapiens chromosome 14 open reading frame 138, mRNA (cDNA clone IMAGE:4831331), partial cds.AK129564 - Homo sapiens cDNA FLJ26053 fis, clone PRS03169.LP895299 - Sequence 163 from Patent EP3253886.JD299673 - Sequence 280697 from Patent EP1572962.AK023982 - Homo sapiens cDNA FLJ13920 fis, clone Y79AA1000420.BX247997 - human full-length cDNA clone CS0DH005YM12 of T cells (Jurkat cell line) of Homo sapiens (human).JD207258 - Sequence 188282 from Patent EP1572962.JD511904 - Sequence 492928 from Patent EP1572962.JD463716 - Sequence 444740 from Patent EP1572962.JD206246 - Sequence 187270 from Patent EP1572962.JD510714 - Sequence 491738 from Patent EP1572962.JD552860 - Sequence 533884 from Patent EP1572962.LF209550 - JP 2014500723-A/17053: Polycomb-Associated Non-Coding RNAs.JD184428 - Sequence 165452 from Patent EP1572962.JD422768 - Sequence 403792 from Patent EP1572962.JD358102 - Sequence 339126 from Patent EP1572962.JD301492 - Sequence 282516 from Patent EP1572962.BC105118 - Homo sapiens chromosome 14 open reading frame 138, mRNA (cDNA clone MGC:132778 IMAGE:8144121), complete cds.BC143673 - Homo sapiens chromosome 14 open reading frame 138, mRNA (cDNA clone MGC:177204 IMAGE:9052187), complete cds.JD053983 - Sequence 35007 from Patent EP1572962.BC143674 - Homo sapiens chromosome 14 open reading frame 138, mRNA (cDNA clone MGC:177205 IMAGE:9052188), complete cds.JD554337 - Sequence 535361 from Patent EP1572962.JD058269 - Sequence 39293 from Patent EP1572962.JD263278 - Sequence 244302 from Patent EP1572962.JD080626 - Sequence 61650 from Patent EP1572962.LF329421 - JP 2014500723-A/136924: Polycomb-Associated Non-Coding RNAs.MA564998 - JP 2018138019-A/136924: Polycomb-Associated Non-Coding RNAs.MA445127 - JP 2018138019-A/17053: Polycomb-Associated Non-Coding RNAs.
Biochemical and Signaling Pathways
Other Names for This Gene
Alternate Gene Symbols: B7ZLA3, B7ZLA4, C14orf138, METTL21D, MT21D_HUMAN, NM_024558, NP_078834, Q2M2X3, Q86T12, Q9H867UCSC ID: uc001wxo.1RefSeq Accession: NM_024558
Protein: Q9H867
(aka MT21D_HUMAN)
CCDS: CCDS9696.2
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
NM_024558.2
exon count:
6 CDS single in 3' UTR:
no
RNA size:
1784
ORF size:
690 CDS single in intron:
no
Alignment % ID:
100.00
txCdsPredict score:
1580.00 frame shift in genome:
no
% Coverage:
100.00
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
no
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
0 # strange splices:
0
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Methods, Credits, and Use Restrictions
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