Human Gene THAP3 (uc001aod.3)
Description: Homo sapiens THAP domain containing, apoptosis associated protein 3 (THAP3), transcript variant 1, mRNA.
Transcript (Including UTRs)
Position: hg19 chr1:6,685,210-6,693,642 Size: 8,433 Total Exon Count: 5 Strand: +
Coding Region
Position: hg19 chr1:6,685,279-6,693,137 Size: 7,859 Coding Exon Count: 5
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Primer design for this transcript
Genetic Association Studies of Complex Diseases and Disorders
Genetic Association Database (archive): THAP3
CDC HuGE Published Literature: THAP3
Comparative Toxicogenomics Database (CTD)
The following chemicals interact with this gene
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
Pfam Domains: PF05485 - THAP domain
ModBase Predicted Comparative 3D Structure on Q8WTV1-3
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse Rat Zebrafish D. melanogaster C. elegans S. cerevisiae
No ortholog No ortholog No ortholog No ortholog No ortholog No ortholog
Gene Details
Gene Sorter
Descriptions from all associated GenBank mRNAs
BC092427 - Homo sapiens THAP domain containing, apoptosis associated protein 3, mRNA (cDNA clone MGC:102992 IMAGE:30376814), complete cds.AK096217 - Homo sapiens cDNA FLJ38898 fis, clone NT2NE2000374.BC022081 - Homo sapiens THAP domain containing, apoptosis associated protein 3, mRNA (cDNA clone IMAGE:4813302), with apparent retained intron.DQ891670 - Synthetic construct clone IMAGE:100004300; FLH179145.01X; RZPDo839D04130D THAP domain containing, apoptosis associated protein 3 (THAP3) gene, encodes complete protein.DQ894856 - Synthetic construct Homo sapiens clone IMAGE:100009316; FLH179141.01L; RZPDo839D04129D THAP domain containing, apoptosis associated protein 3 (THAP3) gene, encodes complete protein.BC005114 - Homo sapiens THAP domain containing, apoptosis associated protein 3, mRNA (cDNA clone IMAGE:4053044), partial cds.JD107794 - Sequence 88818 from Patent EP1572962.JD341642 - Sequence 322666 from Patent EP1572962.JD478896 - Sequence 459920 from Patent EP1572962.JD464595 - Sequence 445619 from Patent EP1572962.LF357477 - JP 2014500723-A/164980: Polycomb-Associated Non-Coding RNAs.JD456080 - Sequence 437104 from Patent EP1572962.LF357476 - JP 2014500723-A/164979: Polycomb-Associated Non-Coding RNAs.JD531198 - Sequence 512222 from Patent EP1572962.JD496217 - Sequence 477241 from Patent EP1572962.MA593054 - JP 2018138019-A/164980: Polycomb-Associated Non-Coding RNAs.MA593053 - JP 2018138019-A/164979: Polycomb-Associated Non-Coding RNAs.
Other Names for This Gene
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
NM_001195752.1
exon count:
5 CDS single in 3' UTR:
no
RNA size:
1308
ORF size:
717 CDS single in intron:
no
Alignment % ID:
100.00
txCdsPredict score:
1634.00 frame shift in genome:
no
% Coverage:
98.70
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
no
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
0 # strange splices:
0
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Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.