Human Gene WDR24 (uc002ciz.1)
  Description: Homo sapiens WD repeat domain 24 (WDR24), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr16:734,702-740,400 Size: 5,699 Total Exon Count: 9 Strand: -
Coding Region
   Position: hg19 chr16:734,734-739,640 Size: 4,907 Coding Exon Count: 9 

Page IndexSequence and LinksPrimersCTDGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther Names
Model InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr16:734,702-740,400)mRNA (may differ from genome)Protein (790 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
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GeneNetworkH-INVHGNCHPRDLynxMGI
PubMedTreefamUniProtKBWikipediaBioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 16.06 RPKM in Testis
Total median expression: 309.38 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -322.60760-0.424 Picture PostScript Text
3' UTR -13.1032-0.409 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  Pfam Domains:
PF00400 - WD domain, G-beta repeat

SCOP Domains:
50952 - Soluble quinoprotein glucose dehydrogenase
50960 - TolB, C-terminal domain
63825 - YWTD domain
63829 - Calcium-dependent phosphotriesterase
69304 - Tricorn protease N-terminal domain
101898 - NHL repeat
50965 - Galactose oxidase, central domain
75011 - 3-carboxy-cis,cis-mucoante lactonizing enzyme
101908 - Putative isomerase YbhE
50969 - YVTN repeat-like/Quinoprotein amine dehydrogenase
50974 - Nitrous oxide reductase, N-terminal domain
50978 - WD40 repeat-like
50993 - Prolyl oligopeptidase, N-terminal domain
69322 - Tricorn protease domain 2
50998 - Quinoprotein alcohol dehydrogenase-like
51004 - C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase
82171 - Dipeptidyl peptidase IV/CD26, N-terminal domain

ModBase Predicted Comparative 3D Structure on Q96S15-2
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologGenome BrowserGenome BrowserGenome BrowserGenome BrowserGenome Browser
Gene DetailsGene Details Gene DetailsGene DetailsGene Details
Gene SorterGene Sorter Gene SorterGene SorterGene Sorter
 RGDEnsemblFlyBaseWormBaseSGD
 Protein SequenceProtein SequenceProtein SequenceProtein SequenceProtein Sequence
 AlignmentAlignmentAlignmentAlignmentAlignment

-  Descriptions from all associated GenBank mRNAs
  BC009761 - Homo sapiens WD repeat domain 24, mRNA (cDNA clone IMAGE:3938571), partial cds.
BC008025 - Homo sapiens WD repeat domain 24, mRNA (cDNA clone MGC:15992 IMAGE:3544791), complete cds.
AK301146 - Homo sapiens cDNA FLJ60907 complete cds, highly similar to WD repeat protein 24.
AL136863 - Homo sapiens mRNA; cDNA DKFZp434F054 (from clone DKFZp434F054).
JD240917 - Sequence 221941 from Patent EP1572962.
AM393299 - Synthetic construct Homo sapiens clone IMAGE:100001883 for hypothetical protein (WDR24 gene).
DQ577998 - Homo sapiens piRNA piR-46110, complete sequence.
JD027562 - Sequence 8586 from Patent EP1572962.
JD028188 - Sequence 9212 from Patent EP1572962.
JD392449 - Sequence 373473 from Patent EP1572962.
JD247513 - Sequence 228537 from Patent EP1572962.
JD254581 - Sequence 235605 from Patent EP1572962.
JD413705 - Sequence 394729 from Patent EP1572962.
JD388755 - Sequence 369779 from Patent EP1572962.
JD059491 - Sequence 40515 from Patent EP1572962.
JD109584 - Sequence 90608 from Patent EP1572962.
JD380674 - Sequence 361698 from Patent EP1572962.
JD099178 - Sequence 80202 from Patent EP1572962.
JD131489 - Sequence 112513 from Patent EP1572962.
JD310676 - Sequence 291700 from Patent EP1572962.
JD109336 - Sequence 90360 from Patent EP1572962.
JD428086 - Sequence 409110 from Patent EP1572962.
JD153551 - Sequence 134575 from Patent EP1572962.
JD396020 - Sequence 377044 from Patent EP1572962.
JD461619 - Sequence 442643 from Patent EP1572962.
JD372454 - Sequence 353478 from Patent EP1572962.
JD124925 - Sequence 105949 from Patent EP1572962.
JD440637 - Sequence 421661 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: C16orf21, JFP7, NM_032259, NP_115635, Q96S15-2
UCSC ID: uc002ciz.1
RefSeq Accession: NM_032259
Protein: Q96S15-2, splice isoform of Q96S15 CCDS: CCDS10420.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_032259.2
exon count: 9CDS single in 3' UTR: no RNA size: 3165
ORF size: 2373CDS single in intron: no Alignment % ID: 99.97
txCdsPredict score: 4788.00frame shift in genome: no % Coverage: 100.00
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.