Human Gene CCDC94 (uc002lzv.4) Description and Page Index
  Description: Homo sapiens coiled-coil domain containing 94 (CCDC94), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr19:4,247,111-4,269,085 Size: 21,975 Total Exon Count: 8 Strand: +
Coding Region
   Position: hg19 chr19:4,247,144-4,268,693 Size: 21,550 Coding Exon Count: 8 

Page IndexSequence and LinksUniProtKB CommentsCTDGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA Descriptions
Other NamesModel InformationMethods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr19:4,247,111-4,269,085)mRNA (may differ from genome)Protein (323 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
BioGPSCGAPEnsemblEntrez GeneExonPrimerGeneCards
neXtProtPubMedStanford SOURCETreefamUniProtKBWikipedia

-  Comments and Description Text from UniProtKB
DESCRIPTION: RecName: Full=Coiled-coil domain-containing protein 94;
SIMILARITY: Belongs to the CWC16 family.
SEQUENCE CAUTION: Sequence=AAC72949.1; Type=Frameshift; Positions=285;

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
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-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 15.40 RPKM in Cells - EBV-transformed lymphocytes
Total median expression: 530.50 RPKM

View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -4.7033-0.142 Picture PostScript Text
3' UTR -162.63392-0.415 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR007590 - CWC16

Pfam Domains:
PF04502 - Family of unknown function (DUF572)

ModBase Predicted Comparative 3D Structure on Q9BW85
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologGenome BrowserGenome BrowserGenome BrowserGenome Browser
Gene Details  Gene DetailsGene DetailsGene Details
Gene Sorter  Gene SorterGene SorterGene Sorter
  Protein SequenceProtein SequenceProtein SequenceProtein Sequence

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0005515 protein binding

-  Descriptions from all associated GenBank mRNAs
  AK001236 - Homo sapiens cDNA FLJ10374 fis, clone NT2RM2001936, weakly similar to 32.3 KD PROTEIN IN CWP1-MBR1 INTERGENIC REGION.
LF341703 - JP 2014500723-A/149206: Polycomb-Associated Non-Coding RNAs.
BC000561 - Homo sapiens coiled-coil domain containing 94, mRNA (cDNA clone MGC:974 IMAGE:3162278), complete cds.
JD147772 - Sequence 128796 from Patent EP1572962.
AK023988 - Homo sapiens cDNA FLJ13926 fis, clone Y79AA1000589, weakly similar to 32.3 KD PROTEIN IN CWP1-MBR1 INTERGENIC REGION.
AF091080 - Homo sapiens clone 614 unknown mRNA, complete sequence.
KJ894239 - Synthetic construct Homo sapiens clone ccsbBroadEn_03633 CCDC94 gene, encodes complete protein.
JD067180 - Sequence 48204 from Patent EP1572962.
JD159307 - Sequence 140331 from Patent EP1572962.
JD097767 - Sequence 78791 from Patent EP1572962.
JD174622 - Sequence 155646 from Patent EP1572962.
JD484784 - Sequence 465808 from Patent EP1572962.
JD162405 - Sequence 143429 from Patent EP1572962.
JD418107 - Sequence 399131 from Patent EP1572962.
JD399383 - Sequence 380407 from Patent EP1572962.
JD424055 - Sequence 405079 from Patent EP1572962.
JD145341 - Sequence 126365 from Patent EP1572962.
JD060694 - Sequence 41718 from Patent EP1572962.
MA577280 - JP 2018138019-A/149206: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: CCD94_HUMAN, NM_018074, NP_060544, O75270, Q9BW85, Q9H862, Q9NW16
UCSC ID: uc002lzv.4
RefSeq Accession: NM_018074
Protein: Q9BW85 (aka CCD94_HUMAN)
CCDS: CCDS12124.1

-  Gene Model Information
category: coding nonsense-mediated-decay: no RNA accession: NM_018074.4
exon count: 8CDS single in 3' UTR: no RNA size: 1441
ORF size: 972CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 1577.00frame shift in genome: no % Coverage: 96.95
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.