Human Gene MIR663A (uc021wbn.1)
  Description: Homo sapiens microRNA 663a (MIR663A), microRNA.
RefSeq Summary (NR_030386): microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]. Sequence Note: This record represents a predicted microRNA stem-loop as defined by miRBase. Some sequence at the 5' and 3' ends may not be included in the intermediate precursor miRNA produced by Drosha cleavage.
Transcript (Including UTRs)
   Position: hg19 chr20:26,188,822-26,188,914 Size: 93 Total Exon Count: 1 Strand: -


Page IndexSequence and LinksPrimersCTDRNA-Seq ExpressionMicroarray Expression
Other SpeciesmRNA DescriptionsOther NamesModel InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr20:26,188,822-26,188,914)mRNA (may differ from genome)No protein
Gene SorterGenome BrowserOther Species FASTATable SchemaBioGPSEnsembl
ExonPrimerHGNCLynxPubMed

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 6.20 RPKM in Testis
Total median expression: 6.50 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Descriptions from all associated GenBank mRNAs
  BC036201 - Homo sapiens hypothetical protein LOC284801, mRNA (cDNA clone IMAGE:4830814).
HZ043263 - JP 2015510401-A/353: MESENCHYMAL STEM CELLS FOR IN VITRO MODELING AND CELL-BASED THERAPY OF HUMAN DISEASES AND BANKS THEREOF.
HZ081889 - JP 2015514392-A/353: MicroRNAS FOR THE GENERATION OF ASTROCYTES.
HZ408743 - JP 2015528002-A/1340: CHIRAL CONTROL.
HZ459435 - WO 2015182781-A/138: Kit or device and method for detecting pancreatic cancer.
HZ460157 - WO 2015190542-A/163: Kit or device and method for detecting biliary tract cancer.
HZ460871 - WO 2015190584-A/368: Kit or device and method for detecting prostate cancer.
HZ461468 - WO 2015190586-A/281: Kit and method for detecting colon cancer.
HZ462119 - WO 2015190591-A/274: Kit and method for detecting breast cancer.
HZ463221 - WO 2015194535-A/315: Kit and method for detecting stomach cancer.
HZ464153 - WO 2015194610-A/589: Kit and method for detecting lung cancer.
HZ464582 - WO 2015194615-A/400: Kit or device and method for detecting hepatic cancer.
HZ465362 - WO 2015194627-A/415: Kit and method for detecting esophageal cancer.
LF404360 - JP 2015509366-A/353: GENERATION OF NEURAL STEM CELLS AND MOTOR NEURONS.
LG052077 - KR 1020150036642-A/1343: CHIRAL CONTROL.
LQ423360 - Sequence 12 from Patent WO2016107933.
LY480875 - KR 1020170010856-A/138: PANCREATIC CANCER DETECTION KIT, DEVICE, AND DETECTION METHOD.
LY495784 - KR 1020170015509-A/163: DETECTION KIT OR DEVICE AND DETECTION METHOD FOR BILIARY TRACT CANCER.
LY496545 - KR 1020170018406-A/415: ESOPHAGEAL CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD.
LY497111 - KR 1020170016485-A/281: COLORECTAL CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD.
LY498054 - KR 1020170018409-A/589: KIT OR DEVICE FOR DETECTING LUNG CANCER, AND LUNG CANCER DETECTION METHOD.
LY498483 - KR 1020170018411-A/400: LIVER CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD.
LY499122 - KR 1020170018412-A/274: BREAST CANCER DETECTION KIT OR DEVICE, AND METHOD FOR DETECTING BREAST CANCER.
LY500034 - KR 1020170019425-A/315: STOMACH CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD.
LY500744 - KR 1020170016490-A/368: PROSTATE CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD.
LZ238737 - WO 2017171048-A/398: Kit, device and method for detecting early pancreatic cancer or precancerous lesion of pancreas.
MA353891 - JP 2018075017-A/353: GENERATION OF NEURAL STEM CELLS AND MOTOR NEURONS.
MS868949 - Sequence 163 from Patent EP3156500.
MS869663 - Sequence 368 from Patent EP3156483.
MS880437 - Sequence 274 from Patent EP3156498.
MS884298 - Sequence 281 from Patent EP3156499.
MS885153 - Sequence 315 from Patent EP3156503.
MS994553 - Sequence 415 from Patent EP3159406.
MS997120 - Sequence 589 from Patent EP3159416.
HZ460302 - WO 2015190542-A/308: Kit or device and method for detecting biliary tract cancer.
HZ461081 - WO 2015190584-A/578: Kit or device and method for detecting prostate cancer.
HZ461671 - WO 2015190586-A/484: Kit and method for detecting colon cancer.
HZ462398 - WO 2015190591-A/553: Kit and method for detecting breast cancer.
HZ463427 - WO 2015194535-A/521: Kit and method for detecting stomach cancer.
HZ464171 - WO 2015194610-A/607: Kit and method for detecting lung cancer.
HZ464840 - WO 2015194615-A/658: Kit or device and method for detecting hepatic cancer.
HZ465597 - WO 2015194627-A/650: Kit and method for detecting esophageal cancer.
LY495929 - KR 1020170015509-A/308: DETECTION KIT OR DEVICE AND DETECTION METHOD FOR BILIARY TRACT CANCER.
LY496780 - KR 1020170018406-A/650: ESOPHAGEAL CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD.
LY497314 - KR 1020170016485-A/484: COLORECTAL CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD.
LY498072 - KR 1020170018409-A/607: KIT OR DEVICE FOR DETECTING LUNG CANCER, AND LUNG CANCER DETECTION METHOD.
LY498741 - KR 1020170018411-A/658: LIVER CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD.
LY499401 - KR 1020170018412-A/553: BREAST CANCER DETECTION KIT OR DEVICE, AND METHOD FOR DETECTING BREAST CANCER.
LY500240 - KR 1020170019425-A/521: STOMACH CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD.
LY500954 - KR 1020170016490-A/578: PROSTATE CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD.
LZ239010 - WO 2017171048-A/671: Kit, device and method for detecting early pancreatic cancer or precancerous lesion of pancreas.
MS869094 - Sequence 308 from Patent EP3156500.
MS869873 - Sequence 578 from Patent EP3156483.
MS880716 - Sequence 553 from Patent EP3156498.
MS884501 - Sequence 484 from Patent EP3156499.
MS885359 - Sequence 521 from Patent EP3156503.
MS994788 - Sequence 650 from Patent EP3159406.
MS997138 - Sequence 607 from Patent EP3159416.
HI964804 - Sequence 89 from Patent WO2010139812.
HI966393 - Sequence 713 from Patent WO2010139811.
HI967259 - Sequence 713 from Patent WO2010139810.
JA049521 - Sequence 17 from Patent WO2011026909.
JA400842 - Sequence 89 from Patent WO2011080318.
JA401820 - Sequence 89 from Patent WO2011080315.
JA402827 - Sequence 89 from Patent WO2011080316.
JA405458 - Sequence 89 from Patent EP2336353.
JA426944 - Sequence 277 from Patent WO2011072177.
JA428984 - Sequence 89 from Patent WO2011095623.
JA682656 - Sequence 124 from Patent WO2011149354.
JA715118 - Sequence 900 from Patent EP2401406.
JA791740 - Sequence 142 from Patent WO2012089772.
JA821190 - Sequence 1711 from Patent EP2285961.
JB022678 - Sequence 520 from Patent WO2013026685.
JB050133 - Sequence 220 from Patent WO2013020926.
JB158072 - Sequence 60 from Patent WO2012142313.
JB249289 - Sequence 57 from Patent EP2478360.
JB620708 - Sequence 688 from Patent WO2013063544.
JB770393 - Sequence 20 from Patent EP2604690.
JC008821 - Sequence 20 from Patent WO2013088338.
JC023576 - Sequence 92 from Patent EP2641976.
JC171993 - Sequence 365 from Patent WO2013150303.
JC515206 - Sequence 5459 from Patent WO2014113089.
JC572804 - Sequence 365 from Patent WO2014125276.
JC582492 - Sequence 365 from Patent WO2014125277.
JC963985 - Sequence 20 from Patent EP2816114.
JE867434 - Sequence 241 from Patent WO2015128671.
JE954188 - Sequence 365 from Patent WO2015052526.
JE955941 - Sequence 365 from Patent WO2015052527.
LP727019 - Sequence 713 from Patent EP2883966.
LP819289 - Sequence 713 from Patent EP3296406.
LP939231 - Sequence 713 from Patent EP3184651.
LQ072794 - Sequence 3118 from Patent EP2964234.
LQ423362 - Sequence 14 from Patent WO2016107933.
LQ724663 - Sequence 296 from Patent WO2018096084.
MS833943 - Sequence 89 from Patent EP3112479.
MS868800 - Sequence 14 from Patent EP3156500.
MS869479 - Sequence 184 from Patent EP3156483.
MS880168 - Sequence 5 from Patent EP3156498.
MS884105 - Sequence 88 from Patent EP3156499.
MS884954 - Sequence 116 from Patent EP3156503.
MS902047 - Sequence 520 from Patent EP3156505.
MS994341 - Sequence 203 from Patent EP3159406.
MS997102 - Sequence 571 from Patent EP3159416.
HZ459552 - WO 2015182781-A/255: Kit or device and method for detecting pancreatic cancer.
LY480992 - KR 1020170010856-A/255: PANCREATIC CANCER DETECTION KIT, DEVICE, AND DETECTION METHOD.
LQ970637 - Sequence 47 from Patent EP2800820.
MP045531 - Sequence 353 from Patent EP3401394.
MP084201 - Sequence 353 from Patent EP3401393.
MP045419 - Sequence 241 from Patent EP3401394.
MP075727 - Sequence 66 from Patent WO2019002265.
MP084089 - Sequence 241 from Patent EP3401393.
MA806261 - WO 2018199275-A/521: Kit, device and method for detection of ovary tumor.
MA806533 - WO 2018199275-A/793: Kit, device and method for detection of ovary tumor.
MA822787 - WO 2019004436-A/600: Kit, device, and method for detection of lung cancer.
MA823137 - WO 2019004436-A/950: Kit, device, and method for detection of lung cancer.
MP129465 - Sequence 365 from Patent EP3470073.
MP162388 - Sequence 365 from Patent WO2019069093.
LY616501 - KR 1020180129785-A/398: KIT OR DEVICE FOR DETECTING EARLY STAGE PANCREATIC CANCER OR PANCREATIC CANCER PRECURSOR LESIONS AND DETECTION METHOD THEREFOR.
LY616774 - KR 1020180129785-A/671: KIT OR DEVICE FOR DETECTING EARLY STAGE PANCREATIC CANCER OR PANCREATIC CANCER PRECURSOR LESIONS AND DETECTION METHOD THEREFOR.
MB473070 - WO 2019208671-A/469: Kit or device and method for detecting bladder cancer.
MB473230 - WO 2019208671-A/629: Kit or device and method for detecting bladder cancer.

-  Other Names for This Gene
  Alternate Gene Symbols: NR_030386
UCSC ID: uc021wbn.1
RefSeq Accession: NR_030386

-  Gene Model Information
 
category: noncoding nonsense-mediated-decay: no RNA accession: NR_030386.1
exon count: 1CDS single in 3' UTR: no RNA size: 93
ORF size: 0CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 153.00frame shift in genome: no % Coverage: 100.00
has start codon: no stop codon in genome: no # of Alignments: 1
has end codon: no retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.