ID:SAMD1_HUMAN DESCRIPTION: RecName: Full=Atherin; AltName: Full=Sterile alpha motif domain-containing protein 1; Short=SAM domain-containing protein 1; FUNCTION: May play a role in atherogenesis by immobilizing LDL in the atherial wall. SUBCELLULAR LOCATION: Cytoplasm. Secreted. TISSUE SPECIFICITY: Expressed in atherosclerotic lesions, not in normal intima. SIMILARITY: Contains 1 SAM (sterile alpha motif) domain. CAUTION: Due to its high GC content it turned out to be difficult to sequence the 5' end of the gene encoding the N-terminal proline-rich region of the protein and to unambiguously determine which sequence is correct. We display the sequence described in PubMed:16159594. This sequence fits better with orthologous sequences but is not consistent with the human reference genome sequence.
ModBase Predicted Comparative 3D Structure on Q6SPF0
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.