Description: Homo sapiens WD repeat domain 66 (CFAP251), transcript variant 1, mRNA. RefSeq Summary (NM_144668): This protein encoded by this gene belongs to the WD repeat-containing family of proteins, which function in the formation of protein-protein complexes in a variety of biological pathways. This family member appears to function in the determination of mean platelet volume (MPV), and polymorphisms in this gene have been associated with variance in MPV. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2011]. Transcript (Including UTRs) Position: hg19 chr12:122,356,463-122,441,832 Size: 85,370 Total Exon Count: 22 Strand: + Coding Region Position: hg19 chr12:122,359,212-122,441,670 Size: 82,459 Coding Exon Count: 21
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q8TBY9
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
