Description: Homo sapiens solute carrier family 18, subfamily B, member 1 (SLC18B1), mRNA. RefSeq Summary (NM_052831): This gene encodes a protein, which has high sequence similarity to rat, xenopus and zebrafish proteins. The protein function is unknown. [provided by RefSeq, Jul 2008]. Transcript (Including UTRs) Position: hg19 chr6:133,090,507-133,119,747 Size: 29,241 Total Exon Count: 14 Strand: - Coding Region Position: hg19 chr6:133,091,409-133,119,595 Size: 28,187 Coding Exon Count: 14
ID:S18B1_HUMAN DESCRIPTION: RecName: Full=MFS-type transporter SLC18B1; AltName: Full=Solute carrier family 18 member B1; SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (Potential). SIMILARITY: Belongs to the major facilitator superfamily.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Pfam Domains: PF07690 - Major Facilitator Superfamily PF12832 - MFS_1 like family
SCOP Domains: 103473 - MFS general substrate transporter
ModBase Predicted Comparative 3D Structure on Q6NT16
Front
Top
Side
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.