Human Gene ZMAT2 (uc003lgy.1)
Description: Homo sapiens zinc finger, matrin-type 2 (ZMAT2), mRNA.
Transcript (Including UTRs)
Position: hg19 chr5:140,080,032-140,086,239 Size: 6,208 Total Exon Count: 6 Strand: +
Coding Region
Position: hg19 chr5:140,080,046-140,085,341 Size: 5,296 Coding Exon Count: 6
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: ZMAT2_HUMAN
DESCRIPTION: RecName: Full=Zinc finger matrin-type protein 2;
SUBCELLULAR LOCATION: Nucleus (Potential).SIMILARITY: Contains 1 matrin-type zinc finger.
Primer design for this transcript
MalaCards Disease Associations
Comparative Toxicogenomics Database (CTD)
The following chemicals interact with this gene
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR015880 - Znf_C2H2-like
IPR022755 - Znf_C2H2_jaz
IPR003604 - Znf_U1
Pfam Domains: PF12171 - Zinc-finger double-stranded RNA-binding
PF12874 - Zinc-finger of C2H2 type
SCOP Domains: 57667 - C2H2 and C2HC zinc fingers
ModBase Predicted Comparative 3D Structure on Q96NC0
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
BC056668 - Homo sapiens zinc finger, matrin type 2, mRNA (cDNA clone MGC:61999 IMAGE:4773709), complete cds.AK055683 - Homo sapiens cDNA FLJ31121 fis, clone IMR322000742, weakly similar to HYPOTHETICAL ZINC FINGER PROTEIN ZK686.4 IN CHROMOSOME III.KJ895679 - Synthetic construct Homo sapiens clone ccsbBroadEn_05073 ZMAT2 gene, encodes complete protein.HQ447705 - Synthetic construct Homo sapiens clone IMAGE:100071033; CCSB013326_01 zinc finger, matrin type 2 (ZMAT2) gene, encodes complete protein.X97303 - H.sapiens mRNA for Ptg-12 protein.JD347904 - Sequence 328928 from Patent EP1572962.JD343538 - Sequence 324562 from Patent EP1572962.JD482892 - Sequence 463916 from Patent EP1572962.JD433636 - Sequence 414660 from Patent EP1572962.JD324668 - Sequence 305692 from Patent EP1572962.JD086516 - Sequence 67540 from Patent EP1572962.JD291981 - Sequence 273005 from Patent EP1572962.JD104841 - Sequence 85865 from Patent EP1572962.JD281878 - Sequence 262902 from Patent EP1572962.JD524194 - Sequence 505218 from Patent EP1572962.JD283936 - Sequence 264960 from Patent EP1572962.JD283877 - Sequence 264901 from Patent EP1572962.JD290478 - Sequence 271502 from Patent EP1572962.
Biochemical and Signaling Pathways
KEGG - Kyoto Encyclopedia of Genes and Genomes hsa03040 - Spliceosome
Other Names for This Gene
Alternate Gene Symbols: NM_144723, NP_653324, Q96NC0, ZMAT2_HUMANUCSC ID: uc003lgy.1RefSeq Accession: NM_144723
Protein: Q96NC0
(aka ZMAT2_HUMAN or ZMA2_HUMAN)
CCDS: CCDS4239.1
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
NM_144723.1
exon count:
6 CDS single in 3' UTR:
no
RNA size:
1512
ORF size:
600 CDS single in intron:
no
Alignment % ID:
99.80
txCdsPredict score:
1400.00 frame shift in genome:
no
% Coverage:
100.00
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
no
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
0 # strange splices:
0
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Methods, Credits, and Use Restrictions
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