Human Gene AMY2A (uc010our.1)
  Description: Homo sapiens amylase, alpha 2A (pancreatic) (AMY2A), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr1:104,257,375-104,262,492 Size: 5,118 Total Exon Count: 6 Strand: +
Coding Region
   Position: hg19 chr1:104,257,497-104,262,490 Size: 4,994 Coding Exon Count: 6 

Page IndexSequence and LinksPrimersGenetic AssociationsMalaCardsCTD
Gene AllelesRNA-Seq ExpressionMicroarray ExpressionRNA StructureOther SpeciesOther Names
Model InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr1:104,257,375-104,262,492)mRNA (may differ from genome)Protein (223 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
EnsemblEntrez GeneExonPrimerGeneCardsH-INVHGNC
LynxMalacardsMGIOMIMPubMedWikipedia
BioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Genetic Association Studies of Complex Diseases and Disorders
  Genetic Association Database (archive): AMY2A
CDC HuGE Published Literature: AMY2A

-  MalaCards Disease Associations
  MalaCards Gene Search: AMY2A
Diseases sorted by gene-association score: pancreatitis (4)

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 348.99 RPKM in Pancreas
Total median expression: 351.74 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -24.86122-0.204 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Other Names for This Gene
  Alternate Gene Symbols: CU675524, NM_000699, NP_000690
UCSC ID: uc010our.1
Representative RNA: CU675524

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: CU675524.1
exon count: 6CDS single in 3' UTR: no RNA size: 1217
ORF size: 669CDS single in intron: no Alignment % ID: 99.11
txCdsPredict score: 1429.00frame shift in genome: no % Coverage: 65.16
has start codon: yes stop codon in genome: no # of Alignments: 2
has end codon: no retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.