Human Gene PI4KAP2 (uc011aie.1)
Description: Homo sapiens phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 2 (PI4KAP2), non-coding RNA.
Transcript (Including UTRs)
Position: hg19 chr22:21,830,665-21,846,383 Size: 15,719 Total Exon Count: 13 Strand: -
Coding Region
Position: hg19 chr22:21,830,874-21,842,641 Size: 11,768 Coding Exon Count: 12
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: B4DSG9_HUMAN
DESCRIPTION: SubName: Full=cDNA FLJ60854, highly similar to Phosphatidylinositol 4-kinase alpha (EC 2.7.1.67);
SIMILARITY: Contains 1 PI3K/PI4K domain.
Primer design for this transcript
Comparative Toxicogenomics Database (CTD)
The following chemicals interact with this gene
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR011009 - Kinase-like_dom
IPR000403 - PI3/4_kinase_cat_dom
IPR018936 - PI3/4_kinase_CS
IPR015433 - PI_Kinase
Pfam Domains: PF00454 - Phosphatidylinositol 3- and 4-kinase
SCOP Domains: 56112 - Protein kinase-like (PK-like)
ModBase Predicted Comparative 3D Structure on B4DSG9
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse Rat Zebrafish D. melanogaster C. elegans S. cerevisiae
No ortholog No ortholog No ortholog No ortholog No ortholog No ortholog
Gene Details
Gene Sorter
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
BC020225 - Homo sapiens phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 2, mRNA (cDNA clone IMAGE:4565073).AK024034 - Homo sapiens cDNA FLJ13972 fis, clone Y79AA1001548, highly similar to PHOSPHATIDYLINOSITOL 4-KINASE ALPHA (EC 2.7.1.67).AK298744 - Homo sapiens cDNA FLJ61336 complete cds, highly similar to Phosphatidylinositol 4-kinase alpha (EC 2.7.1.67).CR456378 - Homo sapiens Em:AP000557.3 full length open reading frame (ORF) cDNA clone (cDNA clone C22ORF:pGEM.Em:AP000557.3.V6).BC141652 - Synthetic construct Homo sapiens clone IMAGE:100000342, MGC:164686 phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 2 (PI4KAP2) mRNA, encodes complete protein.CU013083 - Homo sapiens Em:AP000557.C22.3, mRNA (cDNA clone IMAGE:100000342), complete cds, with stop codon, in Gateway system.KJ904239 - Synthetic construct Homo sapiens clone ccsbBroadEn_13633 PI4KAP2 gene, encodes complete protein.KJ905648 - Synthetic construct Homo sapiens clone ccsbBroadEn_15289 PI4KAP2 gene, encodes complete protein.BC139841 - Homo sapiens similar to phosphatidylinositol 4-kinase alpha, mRNA (cDNA clone IMAGE:100000246), partial cds.CU013371 - Homo sapiens Em:AP000557.C22.3, mRNA (cDNA clone IMAGE:100000246), complete cds, without stop codon, in Gateway system.AK297163 - Homo sapiens cDNA FLJ59121 complete cds, highly similar to Phosphatidylinositol 4-kinase alpha (EC 2.7.1.67).AK299734 - Homo sapiens cDNA FLJ60854 complete cds, highly similar to Phosphatidylinositol 4-kinase alpha (EC 2.7.1.67).AK303215 - Homo sapiens cDNA FLJ57694 complete cds, highly similar to Phosphatidylinositol 4-kinase alpha (EC 2.7.1.67).DI487283 - KR 1020100056450-A/379: DSRNA FOR TREATING VIRAL INFECTION.AK126860 - Homo sapiens cDNA FLJ44912 fis, clone BRAMY3009491, highly similar to Phosphatidylinositol 4-kinase alpha (EC 2.7.1.67).CU676516 - Synthetic construct Homo sapiens gateway clone IMAGE:100019903 5' read PI4KAP2 mRNA.DI487263 - KR 1020100056450-A/359: DSRNA FOR TREATING VIRAL INFECTION.DI487242 - KR 1020100056450-A/338: DSRNA FOR TREATING VIRAL INFECTION.DI487301 - KR 1020100056450-A/397: DSRNA FOR TREATING VIRAL INFECTION.DI487304 - KR 1020100056450-A/400: DSRNA FOR TREATING VIRAL INFECTION.DI487307 - KR 1020100056450-A/403: DSRNA FOR TREATING VIRAL INFECTION.HV593195 - JP 2010532163-A/316: dsRNA for treating viral infection.HW663743 - JP 2013212113-A/212: dsRNA for treating viral infection.JD275230 - Sequence 256254 from Patent EP1572962.JD528084 - Sequence 509108 from Patent EP1572962.JD225880 - Sequence 206904 from Patent EP1572962.DI487258 - KR 1020100056450-A/354: DSRNA FOR TREATING VIRAL INFECTION.JD406145 - Sequence 387169 from Patent EP1572962.JD389964 - Sequence 370988 from Patent EP1572962.JD091914 - Sequence 72938 from Patent EP1572962.
Other Names for This Gene
Alternate Gene Symbols: AK299734, B4DSG9, B4DSG9_HUMANUCSC ID: uc011aie.1RefSeq Accession: NR_003700
Protein: B4DSG9
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
AK299734.1
exon count:
13 CDS single in 3' UTR:
no
RNA size:
1710
ORF size:
1383 CDS single in intron:
no
Alignment % ID:
99.47
txCdsPredict score:
2731.50 frame shift in genome:
no
% Coverage:
98.01
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
no
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
0 # strange splices:
0
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Methods, Credits, and Use Restrictions
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