ID:FA32A_HUMAN DESCRIPTION: RecName: Full=Protein FAM32A; AltName: Full=Ovarian tumor-associated gene 12; Short=OTAG-12; FUNCTION: Isoform 1, but not isoform 2 or isoform 3, may induce G2 arrest and apoptosis. May also increase cell sensitivity to apoptotic stimuli. SUBCELLULAR LOCATION: Isoform 1: Nucleus. SUBCELLULAR LOCATION: Isoform 2: Nucleus. TISSUE SPECIFICITY: Expressed in ovary, with isoform 1 being predominant. INDUCTION: By etoposide, puromycin or carboplatin. SIMILARITY: Belongs to the FAM32 family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Pfam Domains: PF08555 - Eukaryotic family of unknown function (DUF1754)
ModBase Predicted Comparative 3D Structure on Q9Y421
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
