Description: Homo sapiens DPY30 domain containing 1 (DYDC1), transcript variant 2, mRNA. RefSeq Summary (NM_001269053): This gene encodes a member of a family of proteins that contains a DPY30 domain. The encoded protein is involved in acrosome formation during spermatid development. This gene locus overlaps with a closely related gene on the opposite strand. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]. Transcript (Including UTRs) Position: hg19 chr10:82,095,861-82,116,514 Size: 20,654 Total Exon Count: 7 Strand: - Coding Region Position: hg19 chr10:82,095,912-82,112,357 Size: 16,446 Coding Exon Count: 6
ID:DYDC1_HUMAN DESCRIPTION: RecName: Full=DPY30 domain-containing protein 1; FUNCTION: Plays a crucial role during acrosome biogenesis. SUBUNIT: Interacts with SH3GL3. TISSUE SPECIFICITY: Brain and testis. Accumulates during late stage of spermiogenesis. SIMILARITY: Belongs to the dpy-30 family. CAUTION: Sequence AAQ84766 was incorrectly indicated as originating from mouse. SEQUENCE CAUTION: Sequence=BAC86339.1; Type=Miscellaneous discrepancy; Note=Intron retention;
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q8WWB3
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
