Human Gene ARMCX6 (uc004ehy.3)
  Description: Homo sapiens armadillo repeat containing, X-linked 6 (ARMCX6), transcript variant 2, mRNA.
Transcript (Including UTRs)
   Position: hg19 chrX:100,870,108-100,872,991 Size: 2,884 Total Exon Count: 2 Strand: -
Coding Region
   Position: hg19 chrX:100,870,708-100,871,610 Size: 903 Coding Exon Count: 1 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureProtein StructureOther SpeciesGO Annotations
mRNA DescriptionsOther NamesModel InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chrX:100,870,108-100,872,991)mRNA (may differ from genome)Protein (300 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsGeneNetwork
H-INVHGNCHPRDLynxMGIneXtProt
OMIMPubMedTreefamUniProtKBWikipediaBioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: ARMX6_HUMAN
DESCRIPTION: RecName: Full=Protein ARMCX6;
SUBCELLULAR LOCATION: Membrane; Single-pass membrane protein (Potential).
SEQUENCE CAUTION: Sequence=BAA91387.1; Type=Erroneous initiation;

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 18.80 RPKM in Spleen
Total median expression: 467.96 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -77.00263-0.293 Picture PostScript Text
3' UTR -192.58600-0.321 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR006911 - ARM-rpt_dom

Pfam Domains:
PF04826 - Armadillo-like

ModBase Predicted Comparative 3D Structure on Q7L4S7
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGD    
 Protein Sequence    
 Alignment    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Cellular Component:
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0016020 membrane
GO:0016021 integral component of membrane


-  Descriptions from all associated GenBank mRNAs
  LF211662 - JP 2014500723-A/19165: Polycomb-Associated Non-Coding RNAs.
LF211660 - JP 2014500723-A/19163: Polycomb-Associated Non-Coding RNAs.
LF385351 - JP 2014500723-A/192854: Polycomb-Associated Non-Coding RNAs.
AK097018 - Homo sapiens cDNA FLJ39699 fis, clone SMINT2011567, weakly similar to Homo sapiens mRNA for ALEX1.
L20773 - Homo sapiens mRNA in the region near the btk gene involved in a-gamma-globulinemia.
BC007677 - Homo sapiens armadillo repeat containing, X-linked 6, mRNA (cDNA clone MGC:3437 IMAGE:3609980), complete cds.
AK000818 - Homo sapiens cDNA FLJ20811 fis, clone ADSE01435.
LF382266 - JP 2014500723-A/189769: Polycomb-Associated Non-Coding RNAs.
LF382265 - JP 2014500723-A/189768: Polycomb-Associated Non-Coding RNAs.
JD528032 - Sequence 509056 from Patent EP1572962.
JD079789 - Sequence 60813 from Patent EP1572962.
JD186230 - Sequence 167254 from Patent EP1572962.
LF382267 - JP 2014500723-A/189770: Polycomb-Associated Non-Coding RNAs.
LF382264 - JP 2014500723-A/189767: Polycomb-Associated Non-Coding RNAs.
JD408056 - Sequence 389080 from Patent EP1572962.
JD163149 - Sequence 144173 from Patent EP1572962.
JD098093 - Sequence 79117 from Patent EP1572962.
JD367336 - Sequence 348360 from Patent EP1572962.
JD076847 - Sequence 57871 from Patent EP1572962.
JD429428 - Sequence 410452 from Patent EP1572962.
JD085574 - Sequence 66598 from Patent EP1572962.
JD037854 - Sequence 18878 from Patent EP1572962.
HQ447369 - Synthetic construct Homo sapiens clone IMAGE:100070690; CCSB004777_03 armadillo repeat containing, X-linked 6 (ARMCX6) gene, encodes complete protein.
KJ894025 - Synthetic construct Homo sapiens clone ccsbBroadEn_03419 ARMCX6 gene, encodes complete protein.
CU675753 - Synthetic construct Homo sapiens gateway clone IMAGE:100018763 5' read ARMCX6 mRNA.
LF382268 - JP 2014500723-A/189771: Polycomb-Associated Non-Coding RNAs.
LF382262 - JP 2014500723-A/189765: Polycomb-Associated Non-Coding RNAs.
LF382269 - JP 2014500723-A/189772: Polycomb-Associated Non-Coding RNAs.
LF382270 - JP 2014500723-A/189773: Polycomb-Associated Non-Coding RNAs.
LF382271 - JP 2014500723-A/189774: Polycomb-Associated Non-Coding RNAs.
JD498157 - Sequence 479181 from Patent EP1572962.
JD178396 - Sequence 159420 from Patent EP1572962.
JD062524 - Sequence 43548 from Patent EP1572962.
JD265758 - Sequence 246782 from Patent EP1572962.
LF382272 - JP 2014500723-A/189775: Polycomb-Associated Non-Coding RNAs.
JD459105 - Sequence 440129 from Patent EP1572962.
JD121047 - Sequence 102071 from Patent EP1572962.
JD123091 - Sequence 104115 from Patent EP1572962.
JD392130 - Sequence 373154 from Patent EP1572962.
JD512184 - Sequence 493208 from Patent EP1572962.
JD203399 - Sequence 184423 from Patent EP1572962.
JD460345 - Sequence 441369 from Patent EP1572962.
MA620928 - JP 2018138019-A/192854: Polycomb-Associated Non-Coding RNAs.
MA447239 - JP 2018138019-A/19165: Polycomb-Associated Non-Coding RNAs.
MA447237 - JP 2018138019-A/19163: Polycomb-Associated Non-Coding RNAs.
MA617843 - JP 2018138019-A/189769: Polycomb-Associated Non-Coding RNAs.
MA617842 - JP 2018138019-A/189768: Polycomb-Associated Non-Coding RNAs.
MA617844 - JP 2018138019-A/189770: Polycomb-Associated Non-Coding RNAs.
MA617841 - JP 2018138019-A/189767: Polycomb-Associated Non-Coding RNAs.
MA617845 - JP 2018138019-A/189771: Polycomb-Associated Non-Coding RNAs.
MA617839 - JP 2018138019-A/189765: Polycomb-Associated Non-Coding RNAs.
MA617846 - JP 2018138019-A/189772: Polycomb-Associated Non-Coding RNAs.
MA617847 - JP 2018138019-A/189773: Polycomb-Associated Non-Coding RNAs.
MA617848 - JP 2018138019-A/189774: Polycomb-Associated Non-Coding RNAs.
MA617849 - JP 2018138019-A/189775: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: ARMX6_HUMAN, NM_001009584, NP_061880, Q7L4S7, Q9NWJ3
UCSC ID: uc004ehy.3
RefSeq Accession: NM_001009584
Protein: Q7L4S7 (aka ARMX6_HUMAN)
CCDS: CCDS14488.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_001009584.1
exon count: 2CDS single in 3' UTR: no RNA size: 1783
ORF size: 903CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 2006.00frame shift in genome: no % Coverage: 99.05
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: yes # AT/AC introns 0
selenocysteine: no end bleed into intron: 1554# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.