Human Gene GPALPP1 (uc001uzq.3)
  Description: Homo sapiens GPALPP1 (GPALPP1), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr13:45,563,687-45,602,404 Size: 38,718 Total Exon Count: 8 Strand: +
Coding Region
   Position: hg19 chr13:45,563,790-45,602,138 Size: 38,349 Coding Exon Count: 8 

Page IndexSequence and LinksUniProtKB CommentsPrimersGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther Names
Model InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr13:45,563,687-45,602,404)mRNA (may differ from genome)Protein (340 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsGeneNetwork
H-INVHPRDLynxMGIneXtProtPubMed
TreefamUniProtKBWikipediaBioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: K1704_HUMAN
DESCRIPTION: RecName: Full=Uncharacterized protein KIAA1704; AltName: Full=Lipopolysaccharide-specific response protein 7;
SEQUENCE CAUTION: Sequence=AAH17776.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence; Sequence=BAB21795.1; Type=Erroneous initiation;

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 6.42 RPKM in Cells - EBV-transformed lymphocytes
Total median expression: 197.19 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -29.80103-0.289 Picture PostScript Text
3' UTR -51.30266-0.193 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR022226 - DUF3752

Pfam Domains:
PF12572 - Protein of unknown function (DUF3752)

ModBase Predicted Comparative 3D Structure on Q8IXQ4
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGD    
 Protein Sequence    
 Alignment    

-  Descriptions from all associated GenBank mRNAs
  AK304669 - Homo sapiens cDNA FLJ57453 complete cds.
BC017776 - Homo sapiens KIAA1704, mRNA (cDNA clone IMAGE:4699965), partial cds.
BC039586 - Homo sapiens KIAA1704, mRNA (cDNA clone MGC:48766 IMAGE:5722236), complete cds.
AK292493 - Homo sapiens cDNA FLJ76951 complete cds.
AF145122 - Homo sapiens lipopolysaccharide specific response-7 protein (LSR7) mRNA, complete cds.
JD182173 - Sequence 163197 from Patent EP1572962.
BC032333 - Homo sapiens KIAA1704, mRNA (cDNA clone MGC:40283 IMAGE:5169953), complete cds.
AB051491 - Homo sapiens KIAA1704 mRNA for KIAA1704 protein.
AB384264 - Synthetic construct DNA, clone: pF1KSDA1704, Homo sapiens KIAA1704 gene for KIAA1704 protein, complete cds, without stop codon, in Flexi system.
JD134441 - Sequence 115465 from Patent EP1572962.
JD168777 - Sequence 149801 from Patent EP1572962.
JD302185 - Sequence 283209 from Patent EP1572962.
AF245045 - Homo sapiens AD029 mRNA, complete cds.
JD033849 - Sequence 14873 from Patent EP1572962.
JD311422 - Sequence 292446 from Patent EP1572962.
JD298132 - Sequence 279156 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: A8K8X8, AD029, K1704_HUMAN, KIAA1704, LSR7, NM_018559, NP_061029, Q05BX8, Q05D87, Q5T3Z3, Q5T3Z5, Q8IXQ4, Q9C0F9, Q9H2R0, Q9P0W6
UCSC ID: uc001uzq.3
RefSeq Accession: NM_018559
Protein: Q8IXQ4 (aka K1704_HUMAN)
CCDS: CCDS9394.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_018559.2
exon count: 8CDS single in 3' UTR: no RNA size: 1431
ORF size: 1023CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 2246.00frame shift in genome: no % Coverage: 97.27
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 266# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.