Human Gene EXOC3L4 (uc001ymk.3)
Description: Homo sapiens exocyst complex component 3-like 4 (EXOC3L4), mRNA.
Transcript (Including UTRs)
Position: hg19 chr14:103,566,481-103,576,894 Size: 10,414 Total Exon Count: 11 Strand: +
Coding Region
Position: hg19 chr14:103,566,557-103,576,560 Size: 10,004 Coding Exon Count: 11
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: EX3L4_HUMAN
DESCRIPTION: RecName: Full=Exocyst complex component 3-like protein 4;
SIMILARITY: Belongs to the SEC6 family.
Primer design for this transcript
Comparative Toxicogenomics Database (CTD)
The following chemicals interact with this gene
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR010326 - Sec6
Pfam Domains: PF06046 - Exocyst complex component Sec6
ModBase Predicted Comparative 3D Structure on Q17RC7
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
BC113655 - Homo sapiens chromosome 14 open reading frame 73, mRNA (cDNA clone MGC:142215 IMAGE:8322707), complete cds.BC117375 - Homo sapiens chromosome 14 open reading frame 73, mRNA (cDNA clone MGC:150984 IMAGE:40125926), complete cds.HQ258590 - Synthetic construct Homo sapiens clone IMAGE:100073125 chromosome 14 open reading frame 73 (C14orf73) gene, encodes complete protein.KJ905590 - Synthetic construct Homo sapiens clone ccsbBroadEn_15216 EXOC3L4 gene, encodes complete protein.KJ906394 - Synthetic construct Homo sapiens clone ccsbBroadEn_16064 EXOC3L4 gene, encodes complete protein.AK000671 - Homo sapiens cDNA FLJ20664 fis, clone KAIA795.JD391585 - Sequence 372609 from Patent EP1572962.JD461632 - Sequence 442656 from Patent EP1572962.JD370138 - Sequence 351162 from Patent EP1572962.JD368025 - Sequence 349049 from Patent EP1572962.JD060639 - Sequence 41663 from Patent EP1572962.JD481010 - Sequence 462034 from Patent EP1572962.JD478381 - Sequence 459405 from Patent EP1572962.JD140043 - Sequence 121067 from Patent EP1572962.JD164396 - Sequence 145420 from Patent EP1572962.JD163285 - Sequence 144309 from Patent EP1572962.JD471779 - Sequence 452803 from Patent EP1572962.JD124738 - Sequence 105762 from Patent EP1572962.JD095463 - Sequence 76487 from Patent EP1572962.JD147478 - Sequence 128502 from Patent EP1572962.JD518673 - Sequence 499697 from Patent EP1572962.JD275219 - Sequence 256243 from Patent EP1572962.JD108454 - Sequence 89478 from Patent EP1572962.JD545740 - Sequence 526764 from Patent EP1572962.JD492805 - Sequence 473829 from Patent EP1572962.JD376196 - Sequence 357220 from Patent EP1572962.JD347208 - Sequence 328232 from Patent EP1572962.JD334746 - Sequence 315770 from Patent EP1572962.JD186981 - Sequence 168005 from Patent EP1572962.JD065270 - Sequence 46294 from Patent EP1572962.JD246287 - Sequence 227311 from Patent EP1572962.
Other Names for This Gene
Alternate Gene Symbols: C14orf73, EX3L4_HUMAN, NM_001077594, NP_001071062, Q14CR2, Q17RC7UCSC ID: uc001ymk.3RefSeq Accession: NM_001077594
Protein: Q17RC7
(aka EX3L4_HUMAN)
CCDS: CCDS32163.1
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
NM_001077594.1
exon count:
11 CDS single in 3' UTR:
no
RNA size:
2591
ORF size:
2169 CDS single in intron:
no
Alignment % ID:
100.00
txCdsPredict score:
4305.00 frame shift in genome:
no
% Coverage:
99.54
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
no
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
0 # strange splices:
0
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Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.