Human Gene TEX40 (uc009ypm.3) Description and Page Index
  Description: Homo sapiens testis expressed 40 (TEX40), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr11:64,066,818-64,072,239 Size: 5,422 Total Exon Count: 5 Strand: +
Coding Region
   Position: hg19 chr11:64,067,883-64,072,118 Size: 4,236 Coding Exon Count: 5 

Page IndexSequence and LinksUniProtKB CommentsGene AllelesRNA-Seq ExpressionMicroarray Expression
RNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther Names
Model InformationMethods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr11:64,066,818-64,072,239)mRNA (may differ from genome)Protein (200 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsGeneNetwork
OMIMPubMedStanford SOURCEUniProtKB

-  Comments and Description Text from UniProtKB
DESCRIPTION: RecName: Full=Uncharacterized protein C11orf20;
FUNCTION: May be involved in late spermatogenesis (By similarity).

+  Common Gene Haplotype Alleles
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-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 153.05 RPKM in Testis
Total median expression: 208.92 RPKM

View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -500.901065-0.470 Picture PostScript Text
3' UTR -24.10121-0.199 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  ModBase Predicted Comparative 3D Structure on Q9NTU4
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Biological Process:
GO:0007140 male meiosis
GO:0007283 spermatogenesis
GO:0030154 cell differentiation
GO:0030317 flagellated sperm motility
GO:0048240 sperm capacitation

Cellular Component:
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005929 cilium
GO:0016020 membrane
GO:0031514 motile cilium
GO:0036128 CatSper complex
GO:0042995 cell projection
GO:0097228 sperm principal piece

-  Descriptions from all associated GenBank mRNAs
  BC067791 - Homo sapiens potassium channel, subfamily K, member 4, mRNA (cDNA clone IMAGE:30345701), with apparent retained intron.
AF259500 - Homo sapiens two pore K+ channel KT4.1a mRNA, complete cds.
AK296021 - Homo sapiens cDNA FLJ56952 complete cds.
AF247042 - Homo sapiens tandem pore domain potassium channel TRAAK (KCNK4) mRNA, complete cds.
BC033577 - Homo sapiens potassium channel, subfamily K, member 4, mRNA (cDNA clone IMAGE:5200313).
AF259501 - Homo sapiens two pore K+ channel KT4.1b mRNA, complete cds.
BC110327 - Homo sapiens potassium channel, subfamily K, member 4, mRNA (cDNA clone IMAGE:5728354), partial cds.
AF248242 - Homo sapiens 2P domain potassium channel (KCNK4) mRNA, complete cds.
EU978935 - Homo sapiens K2P4.1 potassium channel (KCNK4) mRNA, complete cds.
BC160128 - Synthetic construct Homo sapiens clone IMAGE:100064160, MGC:193243 potassium channel, subfamily K, member 4 (KCNK4) mRNA, encodes complete protein.
JD053443 - Sequence 34467 from Patent EP1572962.
JD125353 - Sequence 106377 from Patent EP1572962.
JD412946 - Sequence 393970 from Patent EP1572962.
JD439586 - Sequence 420610 from Patent EP1572962.
JD356045 - Sequence 337069 from Patent EP1572962.
JD218287 - Sequence 199311 from Patent EP1572962.
JD461919 - Sequence 442943 from Patent EP1572962.
JD140222 - Sequence 121246 from Patent EP1572962.
JD193356 - Sequence 174380 from Patent EP1572962.
JD560859 - Sequence 541883 from Patent EP1572962.
JD544566 - Sequence 525590 from Patent EP1572962.
JD221818 - Sequence 202842 from Patent EP1572962.
JD179179 - Sequence 160203 from Patent EP1572962.
JD158032 - Sequence 139056 from Patent EP1572962.
AL117564 - Homo sapiens mRNA; cDNA DKFZp566E164 (from clone DKFZp566E164).
JD234732 - Sequence 215756 from Patent EP1572962.
AM392988 - Synthetic construct Homo sapiens clone IMAGE:100001694 for hypothetical protein (DKFZP566E164 gene).
AB590987 - Synthetic construct DNA, clone: pFN21AE1116, Homo sapiens C11orf20 gene for chromosome 11 open reading frame 20, without stop codon, in Flexi system.
JD451067 - Sequence 432091 from Patent EP1572962.
DQ578775 - Homo sapiens piRNA piR-46887, complete sequence.
JD476064 - Sequence 457088 from Patent EP1572962.
JD381823 - Sequence 362847 from Patent EP1572962.
JD044443 - Sequence 25467 from Patent EP1572962.
JD168028 - Sequence 149052 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: C11orf20, CK020_HUMAN, NM_001039496, NP_001034585, Q9NTU4
UCSC ID: uc009ypm.3
RefSeq Accession: NM_001039496
Protein: Q9NTU4 (aka CK020_HUMAN)

-  Gene Model Information
category: coding nonsense-mediated-decay: no RNA accession: NM_001039496.1
exon count: 5CDS single in 3' UTR: no RNA size: 764
ORF size: 603CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 667.00frame shift in genome: no % Coverage: 97.38
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
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-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.