Human Gene ZNF367 (uc004awf.3) Description and Page Index
  Description: Homo sapiens zinc finger protein 367 (ZNF367), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr9:99,148,225-99,180,669 Size: 32,445 Total Exon Count: 5 Strand: -
Coding Region
   Position: hg19 chr9:99,150,519-99,180,314 Size: 29,796 Coding Exon Count: 5 

Page IndexSequence and LinksUniProtKB CommentsCTDGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA Descriptions
Other NamesModel InformationMethods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr9:99,148,225-99,180,669)mRNA (may differ from genome)Protein (350 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
BioGPSCGAPEnsemblEntrez GeneExonPrimerGeneCards
GeneNetworkH-INVHGNCHPRDLynxMGI
neXtProtOMIMPubMedStanford SOURCETreefamUniProtKB

-  Comments and Description Text from UniProtKB
  ID: ZN367_HUMAN
DESCRIPTION: RecName: Full=Zinc finger protein 367; AltName: Full=C2H2 zinc finger protein ZFF29;
FUNCTION: Transcriptional activator. Isoform 1 may be involved in transcriptional activation of erythroid genes.
SUBCELLULAR LOCATION: Nucleus.
SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein family.
SIMILARITY: Contains 2 C2H2-type zinc fingers.

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 6.52 RPKM in Cells - EBV-transformed lymphocytes
Total median expression: 48.22 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -184.30355-0.519 Picture PostScript Text
3' UTR -539.052294-0.235 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR007087 - Znf_C2H2
IPR015880 - Znf_C2H2-like
IPR013087 - Znf_C2H2/integrase_DNA-bd

Pfam Domains:
PF00096 - Zinc finger, C2H2 type
PF12874 - Zinc-finger of C2H2 type
PF13894 - C2H2-type zinc finger
PF13912 - C2H2-type zinc finger

SCOP Domains:
57667 - C2H2 and C2HC zinc fingers

ModBase Predicted Comparative 3D Structure on Q7RTV3
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologGenome BrowserGenome BrowserNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGDEnsembl   
 Protein SequenceProtein Sequence   
 AlignmentAlignment   

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0046872 metal ion binding

Biological Process:
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter

Cellular Component:
GO:0005634 nucleus
GO:0005654 nucleoplasm


-  Descriptions from all associated GenBank mRNAs
  LF384929 - JP 2014500723-A/192432: Polycomb-Associated Non-Coding RNAs.
AK091289 - Homo sapiens cDNA FLJ33970 fis, clone DFNES2001564.
LF331874 - JP 2014500723-A/139377: Polycomb-Associated Non-Coding RNAs.
AY554165 - Homo sapiens C2H2 zinc finger protein ZFF29b (ZFF29) mRNA, complete cds, alternatively spliced.
BC126141 - Homo sapiens zinc finger protein 367, mRNA (cDNA clone MGC:161419 IMAGE:8991857), complete cds.
LF331875 - JP 2014500723-A/139378: Polycomb-Associated Non-Coding RNAs.
AY554164 - Homo sapiens C2H2 zinc finger protein ZFF29a (ZFF29) mRNA, complete cds, alternatively spliced.
LF331879 - JP 2014500723-A/139382: Polycomb-Associated Non-Coding RNAs.
LF331881 - JP 2014500723-A/139384: Polycomb-Associated Non-Coding RNAs.
MA620506 - JP 2018138019-A/192432: Polycomb-Associated Non-Coding RNAs.
MA567451 - JP 2018138019-A/139377: Polycomb-Associated Non-Coding RNAs.
MA567452 - JP 2018138019-A/139378: Polycomb-Associated Non-Coding RNAs.
MA567456 - JP 2018138019-A/139382: Polycomb-Associated Non-Coding RNAs.
MA567458 - JP 2018138019-A/139384: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: NM_153695, NP_710162, Q6Q7C8, Q7RTV3, ZFF29, ZN367_HUMAN
UCSC ID: uc004awf.3
RefSeq Accession: NM_153695
Protein: Q7RTV3 (aka ZN367_HUMAN)
CCDS: CCDS6718.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_153695.3
exon count: 5CDS single in 3' UTR: no RNA size: 3714
ORF size: 1053CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 2285.00frame shift in genome: no % Coverage: 99.68
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.